Telomeric repeat binding factor 2

Telomeric repeat binding factor 2

Item
http://www.wikidata.org/entity/Q21109607
TERF2
P688
Mammalian telomeres end in a large duplex loopCell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeresTRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damageEndothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunctionHOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitmentTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2PTOP interacts with POT1 and regulates its localization to telomeresA critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyTRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblastsERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomesPOT1 as a terminal transducer of TRF1 telomere length controlTelomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicasesTelosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsA RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA endsXPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shorteningRPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathwayIn vivo stoichiometry of shelterin componentsTelomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeatsTRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent mannerHuman telomeres contain two distinct Myb-related proteins, TRF1 and TRF2Characterization of the DNA binding specificity of Shelterin complexesTelomere maintenance requires the RAD51D recombination/repair proteinPOT1 and TRF2 cooperate to maintain telomeric integrityA shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteinsSLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with TelomeresMRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length controlFunction of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndromeThe Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2Human XPF controls TRF2 and telomere length maintenance through distinctive mechanismsTRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeresKu86 represses lethal telomere deletion events in human somatic cellsRECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance
P921
Q22009893-3A01BD2A-E3F6-455C-BB38-63C9C042FDD5Q22254585-B51D7E4F-3A8B-4743-900E-3C401540E49EQ24292958-6DC28CEB-98E2-4EB5-AD3D-096BED555C8DQ24292963-B392968A-FACC-480C-A3B7-8DBB7F40C12CQ24293211-729B5501-D0FB-4C03-9CDC-A262A392A893Q24295044-E63C029F-9B98-490B-972D-8375C8AB35F5Q24295162-854B4C86-5CF9-4B46-A6A0-E0214E537442Q24298475-75ABF01C-EFE4-4D95-B855-9D11FA833C2AQ24301264-6FDF9244-D566-4B9A-8C86-8C0A54853A13Q24302611-2DE797CF-692D-4269-AB4E-ECEA5ED225E4Q24302841-2A521909-322A-4A91-848D-1385AE70EC42Q24304488-86F35EAC-D765-4D2E-A0B7-45A722800246Q24304989-580B93AC-48B7-466E-BBF9-579D82702888Q24305452-6A2D39C6-66D3-47B4-A0E2-3DD87792BFD1Q24307902-21908493-F98C-43A5-B1DC-1BED15AACCAFQ24310294-0834E9E9-53FD-45B6-B742-3FEE0B6AA451Q24312021-632DE524-3584-4FAF-B624-4DD517B45361Q24315056-AC6B413C-2943-4F07-B960-F64239F82648Q24317363-FF345F64-D51C-457B-A062-F8F025C7BE30Q24317670-EEBC6C3A-A88F-4790-81CC-430F71289055Q24323345-2BB60C03-5693-4534-A11F-CAB97B0A42F4Q24338140-E1A268DB-8A72-4AC3-9DC7-05088DB6C140Q24338505-A95AE81B-3FDB-4377-B2AF-043757FAF0A4Q27649552-8CE43DF8-C296-4702-BCD3-0B03DB392A6EQ27679884-864F0B3B-7F4C-42D5-8C80-78FC1F9B28F3Q28115619-5BE06E11-8110-444D-90F3-8ECCC4AA8C68Q28116212-1FDC4257-32C8-47FF-93FE-AF5FCA6841D7Q28116237-84FFD258-6AE8-4A68-8E89-B341DD8A921CQ28116315-DF00E522-EF4F-4844-A021-11509F49280EQ28116853-0C0F6B4C-1B0B-4D24-9205-F3E56D9F198BQ28119017-B40342DF-CE94-4B16-AC9F-B0357F1FC5EDQ28771762-0C19F75A-CA67-44E4-AFB6-EB5C1FE7DBC1
P921

Telomeric repeat binding factor 2

Item
http://www.wikidata.org/entity/Q21109607
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Telomeric repeat binding factor 2
@en
Telomeric repeat binding factor 2
@nl
type
label
Telomeric repeat binding factor 2
@en
Telomeric repeat binding factor 2
@nl
altLabel
TERF2
@en
TTAGGG repeat-binding factor 2
@en
telomeric DNA-binding protein
@en
telomeric repeat binding protein 2
@en
telomeric repeat-binding factor 2
@en
prefLabel
Telomeric repeat binding factor 2
@en
Telomeric repeat binding factor 2
@nl
P31
P352
P361
P486
P527
P637
P638
P680
P681
P682
P702
P703
P705
P352
P486
P637
P638
P31
P352
P361
P486
P527
P637
P638
P680
P681
P682
P702
P703
P705