Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response
about
A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevityThe Expanding Landscape of Moonlighting Proteins in YeastsA novel single-cell screening platform reveals proteome plasticity during yeast stress responsesDifferential Protein Distribution between the Nucleus and Mitochondria: Implications in AgingUtilization of Dimethyl Fumarate and Related Molecules for Treatment of Multiple Sclerosis, Cancer, and Other DiseasesReduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasionBacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseasesSelective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory siteUp-regulation of mitochondrial antioxidation signals in ovarian cancer cells with aggressive biologic behavior.Compartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo.Protein profiling of blood samples from patients with hereditary leiomyomatosis and renal cell cancer by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry.Multiple hits for the association of uterine fibroids on human chromosome 1q43.HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.Predicting selective drug targets in cancer through metabolic networks.Differential gene expression in the liver of the African lungfish, Protopterus annectens, after 6 months of aestivation in air or 1 day of arousal from 6 months of aestivation.Effects of excess succinate and retrograde control of metabolite accumulation in yeast tricarboxylic cycle mutants.Protein folding as a driving force for dual protein targeting in eukaryotesEffects of partial silencing of genes coding for enzymes involved in glycolysis and tricarboxylic acid cycle on the enterance of human fibroblasts to the S phase.Genetic insights into OXPHOS defect and its role in cancerBioinformatics analysis and expression study of fumarate hydratase in lung cancer.High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.Multiple proteins with essential mitochondrial functions have glycosylated isoformsLocal generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation.Partitioning of Respiration in an Animal-Algal Symbiosis: Implications for Different Aerobic Capacity between Symbiodinium spp.The mitochondrial component of intracrine action.Crystal structure of an Fe-S cluster-containing fumarate hydratase enzyme from Leishmania major reveals a unique protein foldTwo isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network.Kidney cancer pathology in the new context of targeted therapy.Revisiting the TCA cycle: signaling to tumor formationImpaired TCA cycle flux in mitochondria in skeletal muscle from type 2 diabetic subjects: marker or maker of the diabetic phenotype?HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression.Rare insights into cancer biology.Leiomyoma cutis: a focused review on presentation, management, and association with malignancy.A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.Mitochondrial determinants of cancer health disparities.Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription.Systematic Search for Evidence of Interdomain Horizontal Gene Transfer from Prokaryotes to Oomycete Lineages.Down-regulation of metabolic proteins in hepatocellular carcinoma with portal vein thrombosis.Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.
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P2860
Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@ast
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@en
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@en-gb
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@nl
type
label
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@ast
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@en
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@en-gb
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@nl
prefLabel
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@ast
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@en
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@en-gb
Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@nl
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P2860
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Fumarase: a mitochondrial meta ...... ent of the DNA damage response
@en
P2093
Eitan Shaulian
Esti Singer
Michal Goldberg
Ohad Yogev
Orli Yogev
Thomas D Fox
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1000328
P407
P50
P577
2010-03-01T00:00:00Z