Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
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The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resectionPRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitryDynamic regulation of the COP9 signalosome in response to DNA damageA positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machineryMolecular mechanisms of etoposideThe RNA Splicing Response to DNA DamageATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorRecent findings and technological advances in phosphoproteomics for cells and tissuesEvolution and functional cross-talk of protein post-translational modificationsPhosphoproteomic analyses reveal signaling pathways that facilitate lytic gammaherpesvirus replicationp38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1Variations in brain DNASam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ationActivation of the ATR kinase by the RPA-binding protein ETAA1Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphataseThe human DNA ends proteome uncovers an unexpected entanglement of functional pathwaysThe next level of complexity: crosstalk of posttranslational modifications.Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins.Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to ChemotherapyBenchmarking substrate-based kinase activity inference using phosphoproteomic data.Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stabilityThe LIM domain protein nTRIP6 recruits the mediator complex to AP-1-regulated promoters.A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response.The Ddc1-Mec3-Rad17 sliding clamp regulates histone-histone chaperone interactions and DNA replication-coupled nucleosome assembly in budding yeastA role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks.NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaksMass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cellsProteogenomic convergence for understanding cancer pathways and networks.Metastatic triple-negative breast cancer patient with TP53 tumor mutation experienced 11 months progression-free survival on bortezomib monotherapy without adverse events after ending standard treatments with grade 3 adverse events.The DNA damage response: the omics era and its impact.DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal.Loss of ATM kinase activity leads to embryonic lethality in miceIntegrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancersThe RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damageScreen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.Laser microbeam-induced DNA damage inhibits cell division in fertilized eggs and early embryos.PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage.Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression.
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P2860
Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
description
2012 nî lūn-bûn
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2012年の論文
@ja
2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Proteomic investigations revea ...... P3 in the DNA damage response.
@en
Proteomic investigations revea ...... P3 in the DNA damage response.
@nl
type
label
Proteomic investigations revea ...... P3 in the DNA damage response.
@en
Proteomic investigations revea ...... P3 in the DNA damage response.
@nl
prefLabel
Proteomic investigations revea ...... P3 in the DNA damage response.
@en
Proteomic investigations revea ...... P3 in the DNA damage response.
@nl
P2093
P2860
P50
P1433
P1476
Proteomic investigations revea ...... P3 in the DNA damage response.
@en
P2093
Chunaram Choudhary
Linda Baskcomb
Matthias Mann
Natalia Lukashchuk
Sebastian A Wagner
P2860
P304
P356
10.1016/J.MOLCEL.2012.01.026
P577
2012-03-15T00:00:00Z