ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
about
Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage responseNijmegen breakage syndrome (NBS)Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityChk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restartATM activation by ionizing radiation requires BRCA1-associated BAAT1ATMIN defines an NBS1-independent pathway of ATM signallingWSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activityAcetyltransferase p300 regulates NBS1-mediated DNA damage responseSenataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damageRAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylationHuman Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repairSIRT1 regulates the function of the Nijmegen breakage syndrome proteinTargeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53RAD50 and NBS1 form a stable complex functional in DNA binding and tetheringA role for DEAD box 1 at DNA double-strand breaksThe transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repairDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsMre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activityEssential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesA polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cellCommon mechanisms of PIKK regulationATM, the Mre11/Rad50/Nbs1 complex, and topoisomerase I are concentrated in the nucleus of Purkinje neurons in the juvenile human brainBRCA1 and BRCA2 pathways and the risk of cancers other than breast or ovarianRapid activation of ATR by ionizing radiation requires ATM and Mre11Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation.Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis.DNA Repair and Cytokines: TGF-β, IL-6, and Thrombopoietin as Different Biomarkers of RadioresistanceUbc13: the Lys63 ubiquitin chain building machineTrial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapyActivation of the DNA Damage Response by RNA VirusesA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseDNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of CancerNovel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2The associations between Parkinson's disease and cancer: the plot thickensThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairChromatin perturbations during the DNA damage response in higher eukaryotesRNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break RepairDNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosisGenotoxic anti-cancer agents and their relationship to DNA damage, mitosis, and checkpoint adaptation in proliferating cancer cellsChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising
P2860
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P248
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P2860
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@ast
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@en
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@en-gb
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@nl
type
label
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@ast
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@en
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@en-gb
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@nl
prefLabel
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@ast
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@en
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@en-gb
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@nl
P921
P3181
P356
P1433
P1476
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
@en
P2093
Ji-Hoon Lee
Tanya T Paull
P3181
P356
10.1126/SCIENCE.1108297
P407
P577
2005-04-22T00:00:00Z