Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity - Test2 - elhamkhani - TriplyDB

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

http://www.wikidata.org/entity/Q24644974

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DNA damage triggers genetic exchange in Helicobacter pylori Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response Multiple roles of ATM in monitoring and maintaining DNA integrity DNA resection in eukaryotes: deciding how to fix the break DNA end resection: many nucleases make light work Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damage The DNA Damage Response: Making It Safe to Play with Knives Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing.Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1 Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair EXD2 promotes homologous recombination by facilitating DNA end resection Clinical significance of increased expression of Nijmegen breakage syndrome gene (NBS1) in human primary liver cancer Variants in activators and downstream targets of ATM, radiation exposure, and contralateral breast cancer risk in the WECARE study.Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: effect of exportins and DNA structure Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.DNA damage response in renal ischemia-reperfusion and ATP-depletion injury of renal tubular cells Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications.Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair The MRN complex in double-strand break repair and telomere maintenance.Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2 Aicardi-Goutieres syndrome: from patients to genes and beyond.DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair.ATM signalling and cancer.hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity.Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents.A positive role for c-Abl in Atm and Atr activation in DNA damage response.Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana.Mre11 is expressed in mammalian mitochondria where it binds to mitochondrial DNA.A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons.Mechanism of release and fate of excised oligonucleotides during nucleotide excision repair DNA excision repair: where do all the dimers go?Acetylation-dependent function of human single-stranded DNA binding protein 1.Study of the DNA damage checkpoint using Xenopus egg extracts.Processing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.Focus on histone variant H2AX: to be or not to be.Sharpening the ends for repair: mechanisms and regulation of DNA resection.Signaling of double strand breaks and deprotected telomeres in Arabidopsis

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P2860

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

http://www.wikidata.org/entity/Q24644974

description

2008 nî lūn-bûn

@nan

2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

@ast

Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

@en

Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

@nl

type

label

Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

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Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

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Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

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prefLabel

Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

@ast

Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

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Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

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P1433

The EMBO Journal

P1476

Mre11-Rad50-Nbs1-dependent pro ...... es that stimulate ATM activity

@en

P2093

Alessia Balestrini

http://www.w3.org/2001/XMLSchema#string

Ali Jazayeri

http://www.w3.org/2001/XMLSchema#string

Elizabeth Garner

http://www.w3.org/2001/XMLSchema#string

P2860

Excision of 3' termini by the Trex1 and TREX2 3'-->5' exonucleases. Characterization of the recombinant proteins

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

Human CtIP promotes DNA end resection

Mre11 assembles linear DNA fragments into DNA damage signaling complexes

Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery.

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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1953-62

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scholarly article

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10.1038/EMBOJ.2008.128

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14

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27

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Vincenzo Costanzo

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2008-07-23T00:00:00Z

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5256048

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18596698

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2453060

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