Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes
about
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaksFunctional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joiningModeling the study of DNA damage responses in miceRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationThe response to and repair of RAG-mediated DNA double-strand breaksATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaksFunctional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombinationMechanism of suppression of chromosomal instability by DNA polymerase POLQRif1 prevents resection of DNA breaks and promotes immunoglobulin class switchingInvestigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum.A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden.Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poisonOrigin of chromosomal translocations in lymphoid cancer.HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration.DNA double-strand break signaling and human disorders.Loss of ATM kinase activity leads to embryonic lethality in miceAtaxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation.The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair.Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.Can the DNA damage response be harnessed to modulate atherosclerotic plaque phenotype?Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombinationDocosahexaenoic acid (DHA) sensitizes brain tumor cells to etoposide-induced apoptosisDifferential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte developmentInteraction of cellular proteins with BCL-xL targeted to cytoplasmic inclusion bodies in adenovirus infected cells.H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues.Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1Kinase-dead ATM protein causes genomic instability and early embryonic lethality in miceEnhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53DEK is required for homologous recombination repair of DNA breaks.Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks.DAB2IP regulates autophagy in prostate cancer in response to combined treatment of radiation and a DNA-PKcs inhibitor.ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation.Potential of Radiation-Induced Cellular Stress for Reactivation of Latent HIV-1 and Killing of Infected Cells
P2860
Q24596775-B6F76B4C-6CCF-4800-AA99-48A4AC56A703Q24624166-86091926-2E59-4B78-B12C-4BDBC61035BFQ26826949-835F4A4B-3B20-47E9-93FE-29208AF94FFEQ27000758-6F82DE50-CFFB-4790-8E9A-116B05760C34Q28256889-7B304654-4420-4C25-B48D-A9BBCF1396C8Q28476006-38C58353-1E66-4C10-89B5-7D662A9E6A58Q28508673-732B57F5-4A62-4D83-B6F3-6CC2C9957E16Q28543483-3275EA12-22CD-4EC5-AECA-760B962F84FAQ29465549-14EF2B25-FD99-40A2-8450-19294BA9FD34Q30499891-8B162CAE-A80F-4D48-842F-580971E7B15FQ30806557-5D308845-4BD2-42A1-B1A1-8631437898B1Q33570316-E361F078-A3A9-4B82-BD5B-587EC2B4368FQ33617275-E1F2E84D-8C23-41DC-B0D7-3A55075A8AEDQ33656097-142EF183-C442-4F49-8A1F-8E338DA90162Q33733981-98FEAE40-2FD9-4D34-8027-F7D99275C026Q33803398-C6092080-DC30-4221-A9B8-AB60DF0FBB01Q33832626-2CD20A49-5BDB-4A8F-A853-FE1782E22668Q33870612-3ED3302A-CD96-41A5-9DF2-CCA1E4D2FA65Q34348888-0AB434EA-DE37-4F84-AB6C-324A1CE2EF4AQ34360500-FD11737B-1D75-41CB-B7B6-76C4616E8F8BQ34368454-C8EC756E-BFC8-4055-BC16-C4E8B21D9094Q34549990-138D3F73-CA5F-4031-8EC9-306EE4424B9EQ34550115-055F32F9-C37B-4358-A206-5F054824D996Q34707456-A992F527-5A2D-419B-8CF2-5682D0A30BA6Q34825234-F5BB2542-C1D7-4FD5-9337-3D3C204B178CQ35141697-C3759189-0D96-470B-A120-25CAEFE573BDQ35159001-9F700425-94A1-42F5-8482-247D4447A9A3Q35510360-49A8E740-2976-421E-ABF2-6384FB31422AQ35555378-FD60EA72-A91C-4D08-9652-E10A7F6820ABQ35844884-8A2C222E-ABD0-410D-8DC0-507DEA45B83FQ35893900-2463A85A-795A-4FAD-889F-5BFF4D826734Q36001923-050B306A-3263-43D9-A6C4-09D580356329Q36083139-A9C2EF7C-4AE8-466A-963D-B78F8AB2E104Q36145724-F772B9D7-012C-4F99-8EC7-5EB1D8D99E9DQ36238650-821E1384-E6F4-4CDA-B571-5D8AD3377F84Q36314320-52736E80-F55F-4C19-A81A-2451243F5926Q36349861-33CB2A25-78DD-4BCC-B448-51D97716BA79Q36520723-40AEE11F-72E5-4005-8722-E84A732B6F20Q36544158-D8357A01-106B-4EDE-912D-BA4608317222Q36601890-5FBA8611-13B7-409F-A203-739600FC5C1A
P2860
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@ast
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@en
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@nl
type
label
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@ast
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@en
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@nl
prefLabel
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@ast
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@en
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@nl
P2093
P2860
P3181
P1433
P1476
Essential role for DNA-PKcs in ...... s in ATM-deficient lymphocytes
@en
P2093
André Nussenzweig
Elsa Callén
Frederick W Alt
Gordon Heidkamp
Hua-Tang Chen
Michela Di Virgilio
Mila Jankovic
Nancy Wong
Simone Difilippantonio
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2009.04.025
P407
P577
2009-05-15T00:00:00Z