Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells
about
Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease researchShort mitochondrial ARF triggers Parkin/PINK1-dependent mitophagyPhosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neuronsGaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathiesPharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future ConcernsThe Progress of Induced Pluripotent Stem Cells as Models of Parkinson's DiseaseInduced pluripotent stem cells for modeling neurological disordersEpigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based ModelsInduced pluripotent stem cells in Parkinson's disease: scientific and clinical challengesUnderstanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patientsApplications of Induced Pluripotent Stem Cells in Studying the Neurodegenerative DiseasesUsing iPS Cells toward the Understanding of Parkinson's DiseaseMitochondrial dynamism and heart disease: changing shape and shaping changePatient-specific induced pluripotent stem cells in neurological disease modeling: the importance of nonhuman primate modelsCellular models to investigate biochemical pathways in Parkinson's diseaseiPSCs and small molecules: a reciprocal effort towards better approaches for drug discoveryHuman pluripotent stem cells for modelling human liver diseases and cell therapyProgramming and Reprogramming Cellular Age in the Era of Induced PluripotencyThe pathways of mitophagy for quality control and clearance of mitochondriaNeurodegenerative diseases in a dish: the promise of iPSC technology in disease modeling and therapeutic discoveryPhysiological characterisation of human iPS-derived dopaminergic neuronsAdvances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative DiseasesUtility of Induced Pluripotent Stem Cells for the Study and Treatment of Genetic Diseases: Focus on Childhood Neurological DisordersCell reprogramming and neuronal differentiation applied to neurodegenerative diseases: Focus on Parkinson's diseaseInduced pluripotent stem cell potential in medicine, specifically focused on reproductive medicineEvidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagyExploring new pathways of neurodegeneration in ALS: the role of mitochondria quality controlMorphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathwayUsing C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic ActivityPINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncouplingHigh-throughput screening in primary neuronsMitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and ParkinSolving the puzzle of Parkinson's disease using induced pluripotent stem cells.Induced pluripotent stem cells--opportunities for disease modelling and drug discovery.Investigating human disease using stem cell models.Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplicationStem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells.Modeling human neurological disorders with induced pluripotent stem cells.
P2860
Q21560780-2982A4AA-9F63-4977-BBB4-BDBA7B060542Q24303986-09E187E4-ABF8-4E09-A69F-E1DF8026612BQ24305292-EBA914A6-71B7-4309-A962-D971BE154B15Q24307627-1BE0F905-0895-401F-9E63-70FA4000FD86Q24339508-4B81F5D3-02C7-47D4-87EC-0919D191C8CBQ26745513-1B4E2FA9-313B-4327-AB33-8FF596D47EBFQ26765894-2D68E1CD-FFC8-4805-A754-963FA9BEBC98Q26771402-E466D6E1-6A71-4302-8125-2F01520C3C31Q26772307-1AA5B8B0-69DA-4DB5-9CBE-0556CA4E40A1Q26772879-6182861D-A175-4CF7-9221-26C424044661Q26784399-D89BE0B1-E2BA-4A55-ACCD-580BCDFA2CF1Q26799331-98B07E58-9BE6-4179-BC59-5798D9125D74Q26799590-A1819BC9-A107-4442-B5CE-54A8E9E771ACQ26825299-21538CE4-6A6C-4837-A0A2-E9F62C6D677AQ26825524-AE26993E-C2B1-4489-A0FD-1C62A6CF7C76Q26829742-69B48D24-1F03-448B-B0FB-FD5B58087BF5Q26865055-73D65DDE-CCBA-447A-8D98-1870B7F2557DQ27005360-C9841792-38A0-411A-9439-2CD4CFE96607Q27008903-B1646F2B-9867-4051-B4A4-FC0A7D9E0620Q27009206-760C9156-4C16-499B-AF59-30F255E3CCC1Q27025493-32B8C0F8-75FB-4F16-AC7A-4AFE608E7DF6Q27324718-E56E6FA8-5441-4005-A927-32CAB3BACECEQ28067160-9876BB46-E86F-4DD4-A032-3BDCB3FFBCACQ28080219-DD6EB919-DCF1-484B-B4CB-EFBB2CE3607EQ28080770-59B200B1-76C9-47A7-B489-F6AF621FBC66Q28083057-0AB98A18-526F-4997-AE8E-5070E66182B5Q28258696-F8A68F7D-25D6-4420-95E7-16BE78D248FFQ28387592-6CBE246E-7F53-4D83-8B31-9D6232154CF6Q28391199-A4087187-D74F-4DE4-8175-5F6F9E048DA9Q28396161-09F43704-B0A2-43B3-8ABF-D65562DD4ACAQ28552737-270ED48B-B7C5-4D92-B0EA-1F7E259AB6D5Q28593164-73CB65D7-EFEC-4A52-B7BF-178793597589Q28709230-78DE79F6-BFBB-4C45-B6F5-18B0EEF7F5A4Q30273805-4AA89B76-AF08-4F45-997D-448A8554552DQ33358637-EE19242D-FD61-4EA7-86F9-BA4BDE4EFB50Q34231818-8A381532-38EC-47F6-80C8-1641AA569B07Q34431170-8D906CFE-EDDC-4FE2-8ACF-3BEFF9AFB5C8Q34497765-983AD424-E7FE-49F7-AE9C-2A5CE2CB164DQ34845881-CFD9CCDE-C57C-4B34-9875-084F07F6A6B6Q35056065-9D5423BB-0197-4838-98D6-878A71ED9D3E
P2860
Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@ast
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@en
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@en-gb
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@nl
type
label
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@ast
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@en
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@en-gb
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@nl
prefLabel
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@ast
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@en
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@en-gb
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@nl
P2093
P2860
P3181
P1476
Mitochondrial Parkin recruitme ...... induced pluripotent stem cells
@en
P2093
Dimitri Krainc
Filip Simunovic
Hyun Jeong
John Graziotto
Philip Seibler
P2860
P304
P3181
P356
10.1523/JNEUROSCI.4441-10.2011
P407
P577
2011-04-20T00:00:00Z