Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
about
MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkinShort mitochondrial ARF triggers Parkin/PINK1-dependent mitophagyStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionCross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and DiseaseThe Progress of Induced Pluripotent Stem Cells as Models of Parkinson's DiseaseEpigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based ModelsInduced pluripotent stem cells in Parkinson's disease: scientific and clinical challengesMitochondria: A Therapeutic Target for Parkinson's Disease?Mitochondrial dynamism and heart disease: changing shape and shaping changeAfter the banquet: mitochondrial biogenesis, mitophagy, and cell survivalRole of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagyMitophagy mechanisms and role in human diseasesBeyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial healthMorphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathwayCardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiencyNeuronal Mitophagy in Neurodegenerative DiseasesMitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and ParkinStructure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation.PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease.Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin.Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivoUSP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkinA53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degenerationProfiling of Parkin-binding partners using tandem affinity purification.Modeling human neurological disorders with induced pluripotent stem cells.Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's diseaseAltered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson's Disease Patients.Loss of iron triggers PINK1/Parkin-independent mitophagy.Dynamic survey of mitochondria by ubiquitin.Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?Mitophagy.Parkin and PINK1: much more than mitophagyStem cell reprogramming: basic implications and future perspective for movement disorders.The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?Induced pluripotent stem cell technology for modelling and therapy of cerebellar ataxia.Dysfunction of autophagy as the pathological mechanism of motor neuron disease based on a patient-specific disease model.Targeting autophagy and mitophagy for mitochondrial diseases treatment.Parkin, PINK1 and DJ1 as possible modulators of mTOR pathway in ganglioglioma.
P2860
Q24298771-3F904199-AF5A-44F6-ABEC-799A93C9998AQ24303986-9489CB44-84CC-481C-A02F-6A0A039DE051Q24339442-DCAD6B01-10D2-4647-A456-A8A9FFC4C3A3Q26765684-917CF3DE-51CD-46D6-9EBD-8F5F90B7CE4FQ26765894-4735D63D-B21D-493C-9227-E28E28EE25BAQ26772307-13803E9A-D278-465E-A5AB-9924A5B54E46Q26772879-4715A15F-86CD-4BED-ABC2-E1575B11EFFEQ26784216-551F2F0F-0A86-4234-8B72-7E04C7431584Q26825299-DC29C844-7214-4B7F-A90E-A3D807C4B5CAQ27026657-87093CDE-AA38-445E-AECE-9770142CC642Q27314571-052E0D96-339A-4577-B84E-6BECECA56C3DQ28387592-FB36781A-24B3-4275-AF7D-8CBCFA208222Q28390998-4069929C-22C9-4095-9E84-6C0B3B0DFCD2Q28391455-35F49B6A-C435-4D02-A46F-C08A871CD973Q28396161-E0FBE08C-FA17-4FD5-8212-224B2E5BC85FQ29248109-E4DA427F-9BD1-4701-8523-78BC5AF14B9AQ29248361-D0717286-49F8-4FED-94BF-188FDE1EA4E4Q30273805-DB6EFA53-0421-43B7-A41C-0F7CFE0CC4F7Q30841625-0E096CDB-9A66-4C26-88CE-9A642643A41FQ33619324-0535EA02-8C97-460C-A877-FBBE43157DE6Q34007710-CCCFBFB9-364D-416D-A755-B9807500AA86Q34470315-0456F8F9-8032-4A74-8594-4985CEF8590FQ34815182-8ABCE3B1-280A-4FF1-ACD8-EE4559816931Q34989985-4370CADB-D1C8-4976-AC41-7D64B142B6E8Q35045403-2AB09A24-C5DB-4AA6-B71B-95AC1F8AE305Q35056065-81DEFA88-EA76-4E14-B41B-082CA299443DQ36410154-E74B6ED6-061C-49C6-8A50-A9DA4AB87403Q36611426-71208A5D-DB9A-49BB-9F08-C2898A33E630Q36726882-EA883240-82ED-4927-9267-375757669669Q37693991-A7023426-4519-497B-AEEA-A5E4D91D5408Q37707531-1373F73F-EF91-4B3C-A671-56B65A35B951Q38123809-F88AF5D6-A224-4BF4-95C2-9E21410B40A0Q38144283-9D69093C-C6A8-493F-82C1-6EE2B8FC87DFQ38204824-8331B03D-2140-4C64-BE0E-B4A8D766FDCAQ38302834-35A9DC02-F74D-4A71-8422-75B95BF5ED50Q38374332-2782F0FE-2C24-41D5-9380-234CF6CA4F50Q38542017-60C22CC5-FE9B-4D60-8F81-EE45C1F3DA4CQ38556198-B33F0FB1-4F14-42F4-94B6-CFEE21054C9EQ38622293-0EDBD21B-243D-4097-B372-52A549531BF1Q38627245-6F51E10F-2BAB-428E-90F4-189208ED4F9D
P2860
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
name
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@ast
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@en
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@en-gb
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@nl
type
label
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@ast
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@en
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@en-gb
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@nl
prefLabel
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@ast
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@en
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@en-gb
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@nl
P2093
P2860
P921
P3181
P356
P1476
Phosphatase and tensin homolog ...... tent stem cell-derived neurons
@en
P2093
Aleksandar Rakovic
Alessandra Zanon
Anne Grünewald
Dimitri Krainc
Johann Hagenah
Katharina Shurkewitsch
Philip Seibler
P2860
P304
P3181
P356
10.1074/JBC.M112.391680
P407
P577
2013-01-25T00:00:00Z