Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
about
UBA1: At the Crossroads of Ubiquitin Homeostasis and Neurodegeneration53BP1: pro choice in DNA repairComplementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity.Dissecting the expression landscape of RNA-binding proteins in human cancersEffects of sleep and wake on astrocytes: clues from molecular and ultrastructural studiesCharacterization of ubiquitin-activating enzyme Uba1 in the nucleus by its mammalian temperature-sensitive mutantMass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cellsConjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.UbcH7 regulates 53BP1 stability and DSB repairDNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest.A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.Pathological complete response after cisplatin neoadjuvant therapy is associated with the downregulation of DNA repair genes in BRCA1-associated triple-negative breast cancers.Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatmentDNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.X and Y chromosome complement influence adiposity and metabolism in mice.Quantitative proteomic analyses of mammary organoids reveals distinct signatures after exposure to environmental chemicals.Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer.Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevityDownregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis.Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells.A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.Differences in the expression of cell cycle genes in osteoblasts and endothelial cells cultured on the surfaces of Ti6Al4V and Ti6Al7Nb alloys.Furosine Induced Apoptosis by the Regulation of STAT1/STAT2 and UBA7/UBE2L6 Genes in HepG2 Cells.Recruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling
P2860
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P2860
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
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2012 nî lūn-bûn
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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2012 թվականի ապրիլին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@ast
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@en
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@en-gb
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@nl
type
label
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@ast
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@en
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@en-gb
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@nl
prefLabel
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@ast
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@en
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@en-gb
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
@en
P2093
Libor Macurek
Pavel Moudry
Zdenek Hodny
P2860
P304
P356
10.4161/CC.19978
P407
P577
2012-04-15T00:00:00Z