Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
about
Isoform diversity and regulation in peripheral and central neurons revealed through RNA-SeqNedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage responseA comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromesPTEN suppresses the oncogenic function of AIB1 through decreasing its protein stability via mechanism involving Fbw7 alphaProtein kinases and phosphatases in the control of cell fateSkp2: a novel potential therapeutic target for prostate cancerThe Role of PTEN in Myeloid MalignanciesFocus on PTEN RegulationNuclear PI3K signaling in cell growth and tumorigenesisPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsPhosphoinositides: tiny lipids with giant impact on cell regulationSubcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersCell-type specific roles for PTEN in establishing a functional retinal architectureTherapeutic targeting of cancers with loss of PTEN function.Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesisPTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolismA functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activityCombined phosphatase and tensin homolog (PTEN) loss and fatty acid synthase (FAS) overexpression worsens the prognosis of Chinese patients with hepatocellular carcinomaMolecular mechanisms of long noncoding RNAsSHIP2 multiple functions: a balance between a negative control of PtdIns(3,4,5)P₃ level, a positive control of PtdIns(3,4)P₂ production, and intrinsic docking properties.Plk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cyclePTEN mediates Notch-dependent stalk cell arrest in angiogenesisCdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin.Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.PTEN is a negative regulator of mitotic checkpoint complex during the cell cycleSelf-renewing Pten-/- TP53-/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity.Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell linePTEN modulates miR-21 processing via RNA-regulatory protein RNH1.Determining PTEN functional status by network component deduced transcription factor activitiesPTEN Tumor Suppressor Network in PI3K-Akt Pathway ControlBeta catenin and cytokine pathway dysregulation in patients with manifestations of the "PTEN hamartoma tumor syndrome"Genetically engineered mouse models of PI3K signaling in breast cancer.Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors.PTEN interacts with histone H1 and controls chromatin condensation.p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN.Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.Involvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells.PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma.PTEN: Multiple Functions in Human Malignant Tumors
P2860
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P248
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P2860
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@ast
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@en
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@en-gb
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@nl
type
label
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@ast
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@en
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@en-gb
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@nl
prefLabel
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@ast
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@en
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@en-gb
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Nuclear PTEN regulates the APC ...... phosphatase-independent manner
@en
P2093
Ainara Egia
Arkaitz Carracedo
Min Sup Song
Su Jung Song
P2860
P304
P3181
P356
10.1016/J.CELL.2010.12.020
P407
P577
2011-01-21T00:00:00Z