MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
about
Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent streCdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylationDirect activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.MEKK4 is an effector of the embryonic TRAF4 for JNK activationClostridium difficile toxins: mechanism of action and role in disease.Human mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascadesMip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation.The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathwaysThe MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAILMEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cellsRole of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cellsMEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytesA comprehensive pathway map of epidermal growth factor receptor signalingRETRACTED: TGFβ1 activates c-Jun and Erk1 via αVβ6 integrinTumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivoRegulation of Xenopus gastrulation by ErbB signaling.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.A RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptorsMitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-betaThe mixed lineage kinase DLK utilizes MKK7 and not MKK4 as substrateMEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathwayMEK kinase 2 binds and activates protein kinase C-related kinase 2. Bifurcation of kinase regulatory pathways at the level of an MAPK kinase kinaseTyrosine phosphorylation of the Bcl-2-associated protein BNIP-2 by fibroblast growth factor receptor-1 prevents its binding to Cdc42GAP and Cdc42An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK14-3-3 proteins interact with specific MEK kinasesWhole-genome analysis informs breast cancer response to aromatase inhibitionGrb2 interaction with MEK-kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factorThe MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinasesMolecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPKTrophoblast stem cell maintenance by fibroblast growth factor 4 requires MEKK4 activation of Jun N-terminal kinasePositive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signalingSHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motilityThe diterpenoid alkaloid noroxoaconitine is a Mapkap kinase 5 (MK5/PRAK) inhibitorRho GTPases and their effector proteinsp115 Rho GTPase activating protein interacts with MEKK1.BetaPix-enhanced p38 activation by Cdc42/Rac/PAK/MKK3/6-mediated pathway. Implication in the regulation of membrane ruffling.Stress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factor
P2860
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P2860
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@ast
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@en
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@en-gb
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@nl
type
label
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@ast
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@en
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@en-gb
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@nl
prefLabel
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@ast
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@en
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@en-gb
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@nl
P2093
P2860
P3181
P356
P1433
P1476
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
@en
P2093
G L Johnson
G R Fanger
N L Johnson
P2860
P304
P3181
P356
10.1093/EMBOJ/16.16.4961
P407
P577
1997-08-15T00:00:00Z