Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
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Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation.Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulationWNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertensionApplying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitorsRole of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5NF-kappaB-dependent induction of cathelicidin-related antimicrobial peptide in murine mast cells by lipopolysaccharideMicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1.Cyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signalsMEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via SrcThe role of specific mitogen-activated protein kinase signaling cascades in the regulation of steroidogenesisVascular endothelial growth factor induces MEF2C and MEF2-dependent activity in endothelial cells.The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase LynWiring diagrams of MAPK regulation by MEKK1, 2, and 3.A direct HDAC4-MAP kinase crosstalk activates muscle atrophy programAssessing developmental roles of MKK4 and MKK7 in vitro.miRNA-106a directly targeting RARB associates with the expression of Na(+)/I(-) symporter in thyroid cancer by regulating MAPK signaling pathway.Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsivenessSynoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases.Hepatitis B virus X protein promotes hepatoma cell proliferation via upregulation of MEKK2.Stat3 upregulates MEK5 expression in human breast cancer cells.IL-17A and IL-17F stimulate chemokines via MAPK pathways (ERK1/2 and p38 but not JNK) in mouse cultured mesangial cells: synergy with TNF-alpha and IL-1beta.Interaction with the Paxillin LD1 Motif Relieves MEKK2 Auto-inhibition.MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte-macrophage colony-stimulating factor production in macrophages.Dimerization through the catalytic domain is essential for MEKK2 activation.Noncanonical function of MEKK2 and MEK5 PB1 domains for coordinated extracellular signal-regulated kinase 5 and c-Jun N-terminal kinase signaling.MEKK2 kinase association with 14-3-3 protein regulates activation of c-Jun N-terminal kinase.Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade.
P2860
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P2860
Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
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2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2001 թվականի ապրիլին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@ast
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@en
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@nl
type
label
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@ast
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@en
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@nl
prefLabel
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@ast
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@en
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@nl
P2093
P2860
P3181
P356
P1476
Role of MEKK2-MEK5 in the regu ...... -terminal kinase in mast cells
@en
P2093
E W Gelfand
G L Johnson
S Ganiatsas
T Ishizuka
T P Garrington
P2860
P304
P3181
P356
10.1073/PNAS.081021898
P407
P577
2001-04-10T00:00:00Z