Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function - Test2 - elhamkhani - TriplyDB

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

http://www.wikidata.org/entity/Q24545850

about

The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription Brd4-independent transcriptional repression function of the papillomavirus e2 proteins Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes A Structural Basis for BRD2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus LANA Proteins The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins Viral Genome Tethering to Host Cell Chromatin: Cause and Consequences BET domain co-regulators in obesity, inflammation and cancer Bromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replication Analysis of the papillomavirus E2 and bromodomain protein Brd4 interaction using bimolecular fluorescence complementation Phosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomes Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression Papillomaviruses: a systematic review.Papillomavirus interaction with cellular chromatin.Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4.Role of BRD4 in hematopoietic differentiation of embryonic stem cells.The cellular bromodomain protein Brd4 has multiple functions in E2-mediated papillomavirus transcription activation Recruitment of Brd4 to the human papillomavirus type 16 DNA replication complex is essential for replication of viral DNA.Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses.Small molecule inhibitors of human papillomavirus protein - protein interactions.CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding.Characterization of the functional activities of the bovine papillomavirus type 1 E2 protein single-chain heterodimers.Perturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinoma Replication and partitioning of papillomavirus genomes.HIV-1 Vif promotes the G₁- to S-phase cell-cycle transition.Papillomavirus-Associated Tumor Formation Critically Depends on c-Fos Expression Induced by Viral Protein E2 and Bromodomain Protein Brd4.Recent advances in the search for antiviral agents against human papillomaviruses.An interaction between human papillomavirus 16 E2 and TopBP1 is required for optimum viral DNA replication and episomal genome establishment Dimerization of the papillomavirus E2 protein is required for efficient mitotic chromosome association and Brd4 binding.Structure and acetyl-lysine recognition of the bromodomain.Failure to interact with Brd4 alters the ability of HPV16 E2 to regulate host genome expression and cellular movement The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4 Evolutionary and biophysical relationships among the papillomavirus E2 proteins.Current understanding of the role of the Brd4 protein in the papillomavirus lifecycle.Polybromo-1: the chromatin targeting subunit of the PBAF complex.Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin.The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters.

P2860

Q24319771-3275B1D1-E235-422E-90A0-9C4A857037D9 Q24671845-C9D191CC-57C6-420D-8EDE-4D34679712D5 Q24673761-ADAC1DD9-E043-4D68-9BE5-245E03E49485 Q27680409-556FE53F-D67D-4EEE-A2CA-20552374D109 Q28073961-05C95354-E7E4-45B9-A813-D8B016A4C35E Q28079650-683AE499-4BE3-4B2C-81A8-AC7704E0D89D Q28269301-A6CD0CAC-863A-4904-9D70-B26E7AEFB74E Q28485063-54676E81-CDF4-47A8-909E-F51752BC1DD4 Q28534628-8EC88DB8-6734-43FD-ABDD-BE12596388A2 Q28544058-FF235E59-A52E-4299-81BE-58674A1865D7 Q28551261-54550EA8-F873-4A4D-88E5-8CD5C4BA0FE4 Q33558774-9974C2EA-DDAB-4F53-85B5-BE38FBF1B2A7 Q33617085-71AA129F-D9A9-4901-BCE9-E05DA3BC5E7C Q33729502-0D6F9291-0536-43C6-BBF7-753E42A3B489 Q33734803-E46546EF-1EFB-4E62-AECA-A837F57ED996 Q33865654-CDBD494F-CAFC-45F4-AB43-8A58A2572A89 Q34000419-576CA3AA-516E-4748-8FE1-EFB55E3E8A13 Q34102298-727244BA-3775-4FA9-B568-83AC4102B005 Q34568110-69FF4F04-339B-4987-B13B-32EA8F598FBF Q35053049-6DF6821F-402A-49F8-971C-CB8C2AFD6408 Q35096586-B7503DC6-5E43-40A7-9734-4F07F2D6782C Q35101324-7D3058E5-D599-4246-8F59-0E2026E8BC58 Q35107717-F1B67DB7-E837-464D-8B1B-C3090173EDB8 Q35130275-2584C7E2-A378-4D54-BE91-E4AE6883A45D Q35139675-624CB374-E14C-445E-97A8-F24419646F64 Q35145001-4253599E-B9F8-423E-88E7-6853B4D0E782 Q35150925-142BECE9-7808-4152-8334-3E3BE467537F Q35874198-49289A12-B85E-4D36-803C-EEA29876BF58 Q35884158-C26B8CE1-6E0E-4BBC-AD50-5DB99AD6DB63 Q36284493-07C100F0-63B5-4BF1-B10E-B0428875B695 Q36397627-19D5F83F-8BE0-4586-B67C-56CEAEFF44A4 Q36804570-2B90E98D-BA8E-4406-90FA-665B1CAD259C Q36908432-4B4E6545-F75E-414A-81CB-B98A72308AC1 Q36943823-FF570A19-5763-41DC-9797-5724C4C2DD15 Q36994613-13789452-76B2-4F9F-8EE3-B48CCD288B72 Q36994672-FC731B30-EA6D-4583-BF93-A4AE14DA93CC Q37030691-50E03AF9-D56C-4B56-8579-E7E0E822C3DA Q37107294-DE90A998-133F-46FD-BD8C-BED85DFEC819 Q37110728-A6F0F81B-6DD0-4EF0-95B8-D028545F4D7B Q37157234-EDAEDC07-CC74-40E3-B223-B75FA72ED8B6

P2860

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

http://www.wikidata.org/entity/Q24545850

description

2006 nî lūn-bûn

@nan

2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@ast

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@en

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@nl

type

label

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@ast

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@en

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@nl

prefLabel

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@ast

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@en

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@nl

P1433

Q24545850-940466AC-2687-4B8C-ABE0-68D6B92251BA

P1476

Q24545850-C288941D-A5C1-4767-A95E-13204866F7E1

P2093

Q24545850-0A703100-639C-4471-BCFC-97EC0CB5A266

Q24545850-924A07BE-C853-4715-B9D2-308362D1632B

Q24545850-A7AACDB6-9FB5-47D7-9A1B-B03607CD6BB4

P2860

Q24545850-0181BE81-AF90-41D9-93EA-5C6E5AB9E858

Q24545850-046E4AC8-2E3E-4850-BCD0-703170E731B3

Q24545850-054C0F44-0C2D-4DF9-B785-620B7ACE5B29

Q24545850-06FC911C-D7D2-4C4F-90B6-3146C8DE0041

Q24545850-0C092752-4AB4-4F96-BCF0-24A0710AA627

Q24545850-0DBB5D80-6EAA-4921-99F5-D20AC3E0134A

Q24545850-12531ACF-8EF3-43D9-8056-7F4985FFE890

Q24545850-16E6F835-6091-4FBC-92B3-7C4F63EA987B

Q24545850-22829D83-6736-40B6-9041-7B4966B17189

Q24545850-269BBB09-62BE-478E-9070-14EB2F36BA28

P304

Q24545850-26ABF51D-CFD8-4297-84CD-47A7AFFD0B4E

P31

Q24545850-FAB0D823-E7B2-4DA7-8FCB-5EAACD0F548B

P3181

Q24545850-357D67F1-BA67-4D90-89A0-E1F0B924F799

P356

Q24545850-AD1F900D-EE41-4970-9063-93E0AC918DF8

P407

Q24545850-C2B45634-59E7-4F61-A561-C2710C211D77

P433

Q24545850-1341227D-E3C1-4506-870A-7779B07E71EA

P478

Q24545850-9AB837A2-CB24-41C3-AB61-B2CAD1C14205

P577

Q24545850-6D0AE301-3A15-4997-B48A-9A9188870363

P5875

Q24545850-17BB5FF9-9930-4A42-A6DC-EFFFD6F6A2F5

P698

Q24545850-7792BB28-2817-4D39-BA93-06FEAD258A81

P921

Q24545850-50E78D68-D776-4A4A-97C3-53F814151F1F

P932

Q24545850-5011F604-0AF3-453D-8262-811B10CB0827

P3181

P356

JVI.80.9.4276-4285.2006

P1433

Journal of Virology

P1476

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

@en

P2093

Jianxin You

http://www.w3.org/2001/XMLSchema#string

Michal-Ruth Schweiger

http://www.w3.org/2001/XMLSchema#string

Peter M Howley

http://www.w3.org/2001/XMLSchema#string

P2860

cAMP response element-binding protein-binding protein binds to human papillomavirus E2 protein and activates E2-dependent transcription

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

The mitotic chromosome binding activity of the papillomavirus E2 protein correlates with interaction with the cellular chromosomal protein, Brd4.

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription

Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways

Crystal structure of the human papillomavirus type 18 E2 activation domain

Structure of the intact transactivation domain of the human papillomavirus E2 protein

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

P304

4276-85

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2390695

http://www.w3.org/2001/XMLSchema#string

P356

10.1128/JVI.80.9.4276-4285.2006

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

80

http://www.w3.org/2001/XMLSchema#string

P577

2006-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7168089

http://www.w3.org/2001/XMLSchema#string

P698

16611886

http://www.w3.org/2001/XMLSchema#string

P921

P932

1472042

http://www.w3.org/2001/XMLSchema#string