Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
about
The 3M complex maintains microtubule and genome integrityCUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cellsAn OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterningThe glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradationDisruption of the Fbxw8 gene results in pre- and postnatal growth retardation in miceInduction of cullin 7 by DNA damage attenuates p53 functionAnalysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissuesVascular anomalies: from genetics toward models for therapeutic trialsGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesStructure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceThe SCF ubiquitin ligase: insights into a molecular machineCited1 is required in trophoblasts for placental development and for embryo growth and survivalFbxw8 is essential for Cul1-Cul7 complex formation and for placental developmentPopulation genomics reveal recent speciation and rapid evolutionary adaptation in polar bearsCell-fate determination by ubiquitin-dependent regulation of translationA critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation.Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.Age-dependent transcriptome and proteome following transection of neonatal spinal cord of Monodelphis domestica (South American grey short-tailed opossum)Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.Nedd8 on cullin: building an expressway to protein destruction.VACM-1/cul5 expression in vascular tissue in vivo is induced by water deprivation and its expression in vitro regulates aquaporin-1 concentrations.Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.Cullins and cancer.Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages.Identification of mutations in CUL7 in 3-M syndrome.Expression of a transgene encoding mutant p193/CUL7 preserves cardiac function and limits infarct expansion after myocardial infarctionCytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligasesOncogenic aberrations of cullin-dependent ubiquitin ligases.Epigenetics and microRNAs in preeclampsia.Development of structures and transport functions in the mouse placenta.Cullin RING ligases: glommed by glomulinIdentification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination.Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.Clinical, molecular and histopathological features of short stature syndrome with novel CUL7 mutation in Yakuts: new population isolate in Asia.
P2860
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P2860
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@ast
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@en
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@nl
type
label
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@ast
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@en
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@nl
prefLabel
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@ast
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@en
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@nl
P2093
P2860
P921
P3181
P356
P1476
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
@en
P2093
Chiaki Takahashi
James A DeCaprio
Jeffrey R Skaar
Jocelyn S Kasper
Syed Hamid Ali
Takehiro Arai
P2860
P304
P3181
P356
10.1073/PNAS.1733908100
P407
P577
2003-08-19T00:00:00Z