Nedd8 on cullin: building an expressway to protein destruction. - Test2 - elhamkhani - TriplyDB

Nedd8 on cullin: building an expressway to protein destruction.

Nedd8 on cullin: building an expressway to protein destruction.

http://www.wikidata.org/entity/Q33976667

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Cullin-RING ubiquitin ligases: global regulation and activation cycles Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7 Regulation of nucleolar signalling to p53 through NEDDylation of L11 Ribosomal proteins are targets for the NEDD8 pathway Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51 E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration Control of rapsyn stability by the CUL-3-containing E3 ligase complex Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover NEDD8 acts as a 'molecular switch' defining the functional selectivity of VHL Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates Proximity-induced activation of human Cdc34 through heterologous dimerization.Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation Control of cell growth by the SCF and APC/C ubiquitin ligases Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer Targeting DNA Replication Stress for Cancer Therapy Posttranslational control of HuR function Cullin-RING ligases in regulation of autophagy The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair Building and remodelling Cullin-RING E3 ubiquitin ligases Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases The DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal Development Cellular contractility requires ubiquitin mediated proteolysis Structural basis for the function of DCN-1 in protein Neddylation Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡E2-binding surface on Uba3 β-grasp domain undergoes a conformational transition Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1)

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Nedd8 on cullin: building an expressway to protein destruction.

http://www.wikidata.org/entity/Q33976667

description

2004 nî lūn-bûn

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2004 թուականի Մարտին հրատարակուած գիտական յօդուած

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2004 թվականի մարտին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

@wuu

name

Nedd8 on cullin: building an expressway to protein destruction.

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Nedd8 on cullin: building an expressway to protein destruction.

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type

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Nedd8 on cullin: building an expressway to protein destruction.

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Nedd8 on cullin: building an expressway to protein destruction.

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Nedd8 on cullin: building an expressway to protein destruction.

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Nedd8 on cullin: building an expressway to protein destruction.

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Nedd8 on cullin: building an expressway to protein destruction

@en

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Dora C Dias

http://www.w3.org/2001/XMLSchema#string

Kenneth Wu

http://www.w3.org/2001/XMLSchema#string

Kosj Yamoah

http://www.w3.org/2001/XMLSchema#string

Zhen-Qiang Pan

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

TIP120A associates with cullins and modulates ubiquitin ligase activity

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

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1985-1997

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scholarly article

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10.1038/SJ.ONC.1207414

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11

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23

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2004-03-01T00:00:00Z

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5266633

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1023651648

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15021886

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