about
Cullin family proteins and tumorigenesis: genetic association and molecular mechanismsTargeting the ubiquitin pathway for cancer treatmentBuilding and remodelling Cullin-RING E3 ubiquitin ligasesGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesA Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesisComprehensive assessment of cancer missense mutation clustering in protein structuresOvercoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924CRL4Cdt2: master coordinator of cell cycle progression and genome stabilityCullin 5 destabilizes Cas to inhibit Src-dependent cell transformation.Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinomaThe role of cullin4B in human cancers.The role of the cullin-5 e3 ubiquitin ligase in the regulation of insulin receptor substrate-1.Targeting cullin-RING ligases for cancer treatment: rationales, advances and therapeutic implications.Accelerated hepatocellular carcinoma development in CUL4B transgenic miceCancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosaβ-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells.Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2Targeting neddylation induces DNA damage and checkpoint activation and sensitizes chronic lymphocytic leukemia B cells to alkylating agentsIt Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53.Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.The CUL4A ubiquitin ligase is a potential therapeutic target in skin cancer and other malignancies.Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase.Cullin-RING Ligases as attractive anti-cancer targets.The role of cullin proteins in gastric cancer.E3 ubiquitin ligase Cullin4B mediated polyubiquitination of p53 for its degradation.Effects of the NEDD8-activating enzyme inhibitor MLN4924 on lytic reactivation of Kaposi's sarcoma-associated herpesvirusNetwork-based identification of key proteins involved in apoptosis and cell cycle regulation.CDK-associated Cullin 1 can promote cell proliferation and inhibit cisplatin-induced apoptosis in the AGS gastric cancer cell line.Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924.Mutational analysis of VACM-1/cul5 exons in cancer cell lines.Cullin E3 Ligase Activity Is Required for Myoblast Differentiation.Expression of CUL1 correlates with tumour-grade and recurrence in urothelial carcinoma.
P2860
Q26822657-0240F869-B5C0-4264-8B51-323A32F34353Q26866185-8699225E-E3F8-4C60-9782-98E927AA4B9AQ27027816-C796AE05-5198-4DA6-BA76-B6B288BA3548Q27027897-F1DD105E-FB10-408E-882C-DAAE60F723E0Q27936513-9BC4DFD7-31A4-4941-BE90-437D7EA81ABDQ28262931-3B9FA78E-CCF7-4722-88F8-B05F647EC61EQ28606437-C74DDA33-0C83-40E2-8253-B68D87C7535DQ30410498-C356F2B0-58C5-4281-963B-9E303B976EE5Q30433428-E162061B-C673-428B-B671-0A9ABB5F5CF3Q30577461-77CFC2A0-5819-46B4-9D1E-CD6768D33CACQ33787405-65930633-692C-4225-825B-3BF7B6AEBF49Q33802187-60FD6A2A-150F-4077-A30B-053E7BBF1703Q34035063-2E07E91F-621C-412E-AA7E-755BEFE3C32DQ34043821-B2273287-080B-487A-8096-215A6B61F439Q34043935-E883030F-41EE-45A1-ABA3-11082A90C5F4Q34051772-4CBC30DA-831E-42A8-9B81-463C48BF2D70Q35137658-AC98D19B-1A70-430A-9305-35EB75A166DEQ36152200-F1F66940-A3B4-4092-86FB-95743CAD8CD4Q36293814-60CA8702-ED2A-4D80-B766-58B41E119A69Q36387588-B7C4C8F0-4BE5-4F9D-BEB6-ABF766AB93B7Q37343015-9DE2B855-0025-4AEF-8C9E-295D9DB0CA5CQ37354000-BDEF5712-8993-4354-A8A9-0ECEBA7CDCACQ38058483-AD31BF6A-94BA-44BA-99DE-952F392A5523Q38059746-2FEBFD5C-9B04-4836-81F1-EA471C249434Q38608745-6747C854-0DE1-44C2-906B-975089451CB3Q39031671-34ED1EB1-002F-487B-A4D4-F8F833BCFCA8Q39152964-DE5616C3-2173-4CCD-BE05-C2970D5925DDQ39181880-826432CB-B125-44EF-B806-50D8AC6A2061Q39212145-06643641-5453-4BC3-B0C0-D7D4262C7903Q39451819-350E75EB-10D4-45C5-82DD-4BC54D0BC723Q39531701-25544C8F-8DF5-442B-B9BF-21D719476E28Q45931257-FE21A3AC-9F23-4FF8-9738-B16F4A71AA3DQ51699150-C2D7DD0B-2B95-4E0E-8CA0-3BF4C567CEB2
P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cullins and cancer.
@ast
Cullins and cancer.
@en
Cullins and cancer.
@nl
type
label
Cullins and cancer.
@ast
Cullins and cancer.
@en
Cullins and cancer.
@nl
prefLabel
Cullins and cancer.
@ast
Cullins and cancer.
@en
Cullins and cancer.
@nl
P2860
P356
P1433
P1476
Cullins and cancer.
@en
P2093
Jennifer Lee
Pengbo Zhou
P2860
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
P304
P356
10.1177/1947601910382899
P577
2010-07-01T00:00:00Z