Trafficking regulation of proteins in Alzheimer's disease - Test2 - elhamkhani - TriplyDB

Trafficking regulation of proteins in Alzheimer's disease

Trafficking regulation of proteins in Alzheimer's disease

http://www.wikidata.org/entity/Q26825722

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Amyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta pores Implications of GABAergic Neurotransmission in Alzheimer's Disease The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits.NPTX2 and cognitive dysfunction in Alzheimer's Disease.Alzheimer's disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs.Caffeine Blocks HIV-1 Tat-Induced Amyloid Beta Production and Tau Phosphorylation.Cyclopamine modulates γ-secretase-mediated cleavage of amyloid precursor protein by altering its subcellular trafficking and lysosomal degradation α(2A) adrenergic receptor promotes amyloidogenesis through disrupting APP-SorLA interaction The γ-secretase complex: from structure to function.Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction.Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability.Astrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2 Network Comparison of Inflammation in Colorectal Cancer and Alzheimer's Disease.Appoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology APP Receptor? To Be or Not To Be.Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.Endocytic pathways and endosomal trafficking: a primer Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease.Nicastrin is required for APP but not Notch processing, while Aph-1 is dispensable for processing of both APP and Notch.SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.c-Jun N-terminal Kinase (JNK) induces phosphorylation of amyloid precursor protein (APP) at Thr668, in okadaic acid-induced neurodegeneration.Disrupted-in-Schizophrenia-1 Attenuates Amyloid-β Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of β-Site APP-Cleaving Enzyme 1 Levels.An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.Role of endolysosomes and cholesterol in the pathogenesis of Alzheimer's disease: Insights into why statins might not provide clinical benefit.Rab21, a Novel PS1 Interactor, Regulates γ-Secretase Activity via PS1 Subcellular Distribution.Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer's disease.Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease Not just amyloid: physiological functions of the amyloid precursor protein family.New Insights to Clathrin and Adaptor Protein 2 for the Design and Development of Therapeutic Strategies.SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.Neuroprotective effects of the anticancer drug NVP-BEZ235 (dactolisib) on amyloid-β 1-42 induced neurotoxicity and memory impairment.SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation.Cyclic cis-Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway.Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes.Caffeine, Through Adenosine A3 Receptor-Mediated Actions, Suppresses Amyloid-β Protein Precursor Internalization and Amyloid-β Generation.Role of LDL cholesterol and endolysosomes in amyloidogenesis and Alzheimer's disease.Altered Cholesterol Intracellular Trafficking and the Development of Pathological Hallmarks of Sporadic AD.Defining the minimum substrate and charge recognition model of gamma-secretase.E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion.

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P2860

Trafficking regulation of proteins in Alzheimer's disease

http://www.wikidata.org/entity/Q26825722

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2014 nî lūn-bûn

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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2014 թվականի հունվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Trafficking regulation of proteins in Alzheimer's disease

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Molecular Neurodegeneration

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Trafficking regulation of proteins in Alzheimer's disease

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Guojun Bu

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Huaxi Xu

http://www.w3.org/2001/XMLSchema#string

Shangtong Jiang

http://www.w3.org/2001/XMLSchema#string

Xian Zhang

http://www.w3.org/2001/XMLSchema#string

Yanfang Li

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Yun-wu Zhang

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Creative Commons Attribution 2.0 Generic

P2860

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

Purification and cloning of amyloid precursor protein beta-secretase from human brain

A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi

X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains

Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein

MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.

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10.1186/1750-1326-9-6

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24410826

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Alzheimer's disease

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3891995

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