Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment - Test2 - elhamkhani - TriplyDB

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment

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Structural analysis of the UBA domain of X-linked inhibitor of apoptosis protein reveals different surfaces for ubiquitin-binding and self-association The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex ARTS and Siah collaborate in a pathway for XIAP degradation HECT and RING finger families of E3 ubiquitin ligases at a glance Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation RBR E3 ubiquitin ligases: new structures, new insights, new questions RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination The structure of the catalytic subunit FANCL of the Fanconi anemia core complex RING domain dimerization is essential for RNF4 function A Dual E3 Mechanism for Rub1 Ligation to Cdc53 A RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer Mechanism of ubiquitylation by dimeric RING ligase RNF4 Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3 Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity Gid9, a second RING finger protein contributes to the ubiquitin ligase activity of the Gid complex required for catabolite degradation.Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 E2s: structurally economical and functionally replete Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G The ability of TRIM3 to induce growth arrest depends on RING-dependent E3 ligase activity A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125 Hexagonal assembly of a restricting TRIM5alpha protein Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.Structural and functional insights to ubiquitin-like protein conjugation.Comprehensively surveying structure and function of RING domains from Drosophila melanogaster Inhibitor of Apoptosis (IAP) proteins as drug targets for the treatment of cancer Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structure The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation Host insect inhibitor-of-apoptosis SfIAP functionally replaces baculovirus IAP but is differentially regulated by Its N-terminal leader.Domain organization of XAF1 and the identification and characterization of XIAP(RING) -binding domain of XAF1.

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P2860

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment

http://www.wikidata.org/entity/Q27652077

description

2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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Journal of Biological Chemistry

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Structures of the cIAP2 RING d ...... gating enzyme (E2) recruitment

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P2093

Clyde A Smith

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Frances-Rose Schumacher

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Katrin Linke

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Rebecca Feltham

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P2860

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

An essential function of the extreme C-terminus of MDM2 can be provided by MDMX

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites

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31633-40

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scholarly article

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91420

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10.1074/JBC.M804753200

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P433

46

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283

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Catherine L. Day

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2008-11-14T00:00:00Z

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18784070

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