Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies - Test2 - elhamkhani - TriplyDB

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

http://www.wikidata.org/entity/Q27679353

about

A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union The evolution within us Structural insights on the role of antibodies in HIV-1 vaccine and therapy HIV broadly neutralizing antibody targets Antigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cells Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1 HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design Deconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and Immunity Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site Antiviral Therapy by HIV-1 Broadly Neutralizing and Inhibitory Antibodies Broadly Neutralizing Antibodies for HIV Eradication Perspectives for immunotherapy: which applications might achieve an HIV functional cure?HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth What Are the Most Powerful Immunogen Design Vaccine Strategies?Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Computational tools for epitope vaccine design and evaluation Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.Free Energy Perturbation Calculation of Relative Binding Free Energy between Broadly Neutralizing Antibodies and the gp120 Glycoprotein of HIV-1.Clonify: unseeded antibody lineage assignment from next-generation sequencing data Broadly Neutralizing Antibodies as Treatment: Effects on Virus and Immune System Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates The promise and challenge of high-throughput sequencing of the antibody repertoire.Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline.The Antibody Germline/Maturation Hypothesis, Elicitation of Broadly Neutralizing Antibodies Against HIV-1 and Cord Blood IgM Repertoires Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies.Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption.Neutralizing Monoclonal Antibodies to Fight HIV-1: On the Threshold of Success.Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies.Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.Emerging concepts on T follicular helper cell dynamics in HIV infection HIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.

P2860

Q24568048-87D1C00F-78ED-43C1-BADB-83AC2204F50A Q26801603-730F4CB0-FCAA-4223-A60E-89D1D46D1E91 Q26829461-304DDD9B-EE12-4E06-AB97-B5FD3EC7B2E3 Q27026662-0B1BC754-EB83-4E39-AADD-39F2A54F286A Q27320687-6EF43AE3-DAF0-47AC-84A3-84C7F64E86CD Q27322403-EA067B34-3F7C-4139-921A-6BF903A1765B Q27324184-5B3098B5-D38B-4638-ACD5-5C6C61560CE2 Q27643993-EA81479C-CF3A-4D21-B077-7E6D8B77CFBB Q27644544-1C8EC1D2-9CF3-4152-988A-ACAE753E14F7 Q27644634-BE7BAAB2-D5E2-4787-9D0F-624CCAD1488B Q27654848-A5A994C4-63C9-4EC9-B744-70838C8B2A5D Q27684503-48D66B8E-1524-4608-A962-A964B2EC0E71 Q27684529-A3F1CF9D-7C69-4BE5-8550-225F735DF102 Q27704710-99473399-2161-4540-838E-6C862910A657 Q27723297-A663398A-7CEA-49FE-8D76-62B737BD82D3 Q27728037-ABA9355D-188D-43D7-9607-D5DEDB8A8561 Q28066335-2B178FA9-E513-407A-902C-9969862B5B85 Q28073939-6F0B24FA-5A84-46F7-AAD4-27BB4796DD4E Q28078726-0860E467-798B-4C26-8092-0B2B55D2FD95 Q28086826-E55384EA-C3C9-4824-AF56-7AE20CC5F6DE Q28729792-5AE975F9-C910-4EC3-814E-72C9A35EC55A Q30234773-8C3EAF43-CFE7-4814-922B-67A3F8E387BC Q30373339-F07C6017-4C67-4922-B284-71677D919BB6 Q30391094-59D0CA28-A895-489B-8CC6-E2C6126D24F7 Q30395868-4941DCD8-809B-4581-B89A-D762CB64C672 Q31082802-C2A5C105-1D18-4D2A-ACBC-1BF7088324D3 Q33592852-7FF1D24E-6F07-41A6-A4EA-57168A6C66A2 Q33612459-08E3E4FE-5814-4EC3-8E4A-52531350617D Q33962293-E5317F6A-F3A8-4739-B249-B8BB7F99C799 Q34075820-66085050-9725-4BC6-B62D-17B2B5C73FDB Q34101087-E2747FEC-A989-433B-90F0-8E0534E3CF24 Q34114798-373FE598-42B6-4EDC-BC77-780710CE2CFF Q34177732-3AE15379-82CE-413F-9091-86CAFD12BD2A Q34531858-7137719C-9CB4-4D2E-894A-AA541AD9F4EB Q34550046-57097C29-51AC-4C18-B6F8-BC2AB830C8E3 Q34593647-BDC0F8B2-DA42-4484-A3B9-3FB9F4DAC3CF Q34593860-47A620DB-5654-4A9F-92F4-5244CBBF233F Q34687653-DED455DE-25A2-4DF3-9AC4-A11199173543 Q34915786-1E6E071A-F560-42DA-A083-0839C9CBCD2F Q35073270-B7E980E9-5625-4559-8113-2980FAC78FDD

P2860

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

http://www.wikidata.org/entity/Q27679353

description

2013 nî lūn-bûn

@nan

2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@ast

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@en

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@nl

type

label

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@ast

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@en

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@nl

prefLabel

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@ast

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@en

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@nl

P1433

Q27679353-8AD03386-103B-46FF-B452-FC41D57C9ADD

P1476

Q27679353-114D440E-2FA4-41BA-AFFB-60EF9DD30F3F

P2093

Q27679353-178B500B-4BC5-42CE-863D-15CC9254F5B7

Q27679353-189D1454-3028-4C36-B4EF-9F982CD6297E

Q27679353-1FAA5DD2-5085-4308-8FA7-2B4FA2122FA2

Q27679353-2A63B18B-F8E5-4365-9F0D-3F447370C3D5

Q27679353-3F11B7C0-E5F0-4B42-AB1F-3556C4547249

Q27679353-43E46327-1DFC-4F95-9F21-FDEBD1CDDCAF

Q27679353-5BC9F57B-B85D-4D00-8565-F31FCFCA37E6

Q27679353-5D6C25FC-A071-47E6-AC5E-AB73EC1E728D

Q27679353-619690DA-8884-48AD-B87D-9454057C309E

Q27679353-693055D9-8517-4868-9F9D-3F27574A39CA

P2860

Q27679353-091CD95E-B93F-4F1D-815B-D0EDB1658A08

Q27679353-1068B69B-2DFC-44F8-BD8D-B9509D792599

Q27679353-179B80D1-99A2-4FAB-B5F2-B7C31BF2C821

Q27679353-189065B6-18DA-4A4F-89A5-D7FC2B6EBA3D

Q27679353-1AADDE54-79B0-4BB9-9B9B-937F3A1F0BE0

Q27679353-1F83AA97-3276-4C0C-A695-6C45BF9BB831

Q27679353-23B28EB1-7CDF-4D06-A2D3-42FB53C75487

Q27679353-2B5FA9BB-A8D1-4C1C-ADC0-074D3625F6BA

Q27679353-2C0AF283-0EBF-43E0-8A1A-640E45278CD8

Q27679353-313ABE9D-AD7D-43DD-B3E4-05F24A25E8A2

P304

Q27679353-80AC5090-F4D9-47FE-931E-0E82BCEDC9A7

P31

Q27679353-FE1468F9-19FD-42C8-B914-BC7D3EBE1F6C

P3181

Q27679353-7F3FF7F7-339E-477E-BEC6-2C6BDA8DBFBD

P356

Q27679353-42E08AD7-E8E9-45BC-849A-D5CC28A0BFD5

P407

Q27679353-027D6AB0-B1A3-4048-83F8-FD17534D3824

P433

Q27679353-332E0450-20DD-4FF6-8F4C-3C22E3D5C6C2

P478

Q27679353-B34029D1-5396-4FB7-A116-26533C1C8CF7

P50

Q27679353-198467A7-DBEB-48C4-B0F1-C864874320CC

Q27679353-59B24270-1239-4EF9-A87D-710C508F31E3

Q27679353-71B4D2D9-C80B-4A70-ABD4-550DF5235462

Q27679353-8C279121-7773-4016-AE11-43DBD9E96336

Q27679353-A440C88D-47DE-4F64-A45F-89E9C4461151

Q27679353-AC38A37A-7E24-440F-8180-0BE7CE0056B7

Q27679353-ACC1E0F8-6665-4DFC-BC1A-247C7249910C

Q27679353-D871AD9C-1B82-46CE-AC6B-7B5BE9315EF8

Q27679353-F342451B-13B4-4D8B-9C26-19F9847933ED

P577

Q27679353-E8BDC5B9-884F-47F1-B858-8C3B93CE574E

P698

Q27679353-C7303BB3-8449-4EC8-835F-B72CE0712598

P921

Q27679353-E624AB1C-B389-4E8B-96B4-839C0B8600E2

P932

Q27679353-2D9ACAE4-5473-40F1-9AB2-8FCB15BF3AAA

P3181

P356

J.IMMUNI.2013.04.012

P1433

P1476

Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies

@en

P2093

Anqi Zheng

http://www.w3.org/2001/XMLSchema#string

Baoshan Zhang

http://www.w3.org/2001/XMLSchema#string

Chaim A Schramm

http://www.w3.org/2001/XMLSchema#string

Dennis R Burton

http://www.w3.org/2001/XMLSchema#string

Gwo-Yu Chuang

http://www.w3.org/2001/XMLSchema#string

Han R Altae-Tran

http://www.w3.org/2001/XMLSchema#string

Ivelin S Georgiev

http://www.w3.org/2001/XMLSchema#string

Jiang Zhu

http://www.w3.org/2001/XMLSchema#string

Johannes F Scheid

http://www.w3.org/2001/XMLSchema#string

Krisha McKee

http://www.w3.org/2001/XMLSchema#string

P2860

X-ray snapshots of the maturation of an antibody response to a protein antigen

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

Structural and genetic basis for development of broadly neutralizing influenza antibodies

Coot: model-building tools for molecular graphics

Phasercrystallographic software

P304

245-58

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

445786

http://www.w3.org/2001/XMLSchema#string

P356

10.1016/J.IMMUNI.2013.04.012

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

39

http://www.w3.org/2001/XMLSchema#string

P50

Michel C. Nussenzweig

Lawrence Shapiro

Stephanie Moquin

James C Mullikin

P577

2013-08-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23911655

http://www.w3.org/2001/XMLSchema#string

P921

P932

3985390

http://www.w3.org/2001/XMLSchema#string