Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
about
A structurally distinct human mycoplasma protein that generically blocks antigen-antibody unionThe evolution within usStructural insights on the role of antibodies in HIV-1 vaccine and therapyHIV broadly neutralizing antibody targetsAntigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cellsMolecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunizationStructural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 DonorsVaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A VirusesStructures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine designDeconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and ImmunityAffinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domainsNeutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptorTrimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and GSomatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing AntibodiesNatively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding siteAntiviral Therapy by HIV-1 Broadly Neutralizing and Inhibitory AntibodiesBroadly Neutralizing Antibodies for HIV EradicationPerspectives for immunotherapy: which applications might achieve an HIV functional cure?HIV-1 gp120 as a therapeutic target: navigating a moving labyrinthWhat Are the Most Powerful Immunogen Design Vaccine Strategies?Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Computational tools for epitope vaccine design and evaluationGeneration of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.Free Energy Perturbation Calculation of Relative Binding Free Energy between Broadly Neutralizing Antibodies and the gp120 Glycoprotein of HIV-1.Clonify: unseeded antibody lineage assignment from next-generation sequencing dataBroadly Neutralizing Antibodies as Treatment: Effects on Virus and Immune SystemVaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman PrimatesThe promise and challenge of high-throughput sequencing of the antibody repertoire.Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline.The Antibody Germline/Maturation Hypothesis, Elicitation of Broadly Neutralizing Antibodies Against HIV-1 and Cord Blood IgM RepertoiresCooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies.Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodiesHIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption.Neutralizing Monoclonal Antibodies to Fight HIV-1: On the Threshold of Success.Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies.Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.Emerging concepts on T follicular helper cell dynamics in HIV infectionHIV antibodies. Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies.Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.
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P2860
Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
description
2013 nî lūn-bûn
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2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
@ast
Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
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Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
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Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
@ast
Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
@en
Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
@nl
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Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
@ast
Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
@en
Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
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Multidonor Analysis Reveals St ...... tion by VRC01-Class Antibodies
@en
P2093
Anqi Zheng
Baoshan Zhang
Chaim A Schramm
Dennis R Burton
Gwo-Yu Chuang
Han R Altae-Tran
Ivelin S Georgiev
Johannes F Scheid
Krisha McKee
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P304
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P356
10.1016/J.IMMUNI.2013.04.012
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P577
2013-08-22T00:00:00Z