MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.
about
SIRT1 negatively regulates the mammalian target of rapamycinRapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevityExtending healthy life span--from yeast to humansLessons on longevity from budding yeastmTOR is a key modulator of ageing and age-related diseaseChemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processesReplicative and chronological aging in Saccharomyces cerevisiae.mTOR signaling in growth control and diseaseCalorie restriction and the exercise of chromatinInhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and BeyondDeveloping criteria for evaluation of geroprotectors as a key stage toward translation to the clinicBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesCaloric restriction: is mammalian life extension linked to p53?The many ways to age for a single yeast cellThe yeast transcription factor Crz1 is activated by light in a Ca2+/calcineurin-dependent and PKA-independent manner.Regulation of ribosomal DNA amplification by the TOR pathway.Casein kinase II regulation of the Hot1 transcription factor promotes stochastic gene expressionEnvironment-responsive transcription factors bind subtelomeric elements and regulate gene silencing.Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment.Communications between Mitochondria, the Nucleus, Vacuoles, Peroxisomes, the Endoplasmic Reticulum, the Plasma Membrane, Lipid Droplets, and the Cytosol during Yeast Chronological AgingDepletion of Rictor, an essential protein component of mTORC2, decreases male lifespanRapalogs and mTOR inhibitors as anti-aging therapeuticsHaploinsufficiency of akt1 prolongs the lifespan of miceIncreased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expressioncuTauLeaping: a GPU-powered tau-leaping stochastic simulator for massive parallel analyses of biological systemsSix plant extracts delay yeast chronological aging through different signaling pathwaysMammalian sirtuins: biological insights and disease relevanceTissue vitamin concentrations are maintained constant by changing the urinary excretion rate of vitamins in rats' restricted food intake.Yeast sirtuins and the regulation of aging.Calorie restriction effects on silencing and recombination at the yeast rDNA.Calorie restriction reduces rDNA recombination independently of rDNA silencing.Frequency-modulated nuclear localization bursts coordinate gene regulation.Using movies to analyse gene circuit dynamics in single cellsSignal-dependent dynamics of transcription factor translocation controls gene expression.Molecular phenotyping of aging in single yeast cells using a novel microfluidic devicePulsatile dynamics in the yeast proteome.Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast.Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila.Validation of anti-aging drugs by treating age-related diseases.Growth and aging: a common molecular mechanism.
P2860
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P2860
MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@ast
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@en
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@nl
type
label
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@ast
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@en
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@nl
prefLabel
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@ast
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@en
MSN2 and MSN4 link calorie res ...... n in Saccharomyces cerevisiae.
@nl
P2860
P921
P3181
P1433
P1476
MSN2 and MSN4 link calorie res ...... on in Saccharomyces cerevisiae
@en
P2093
Keyman D Kim
Oliver Medvedik
P2860
P3181
P356
10.1371/JOURNAL.PBIO.0050261
P407
P577
2007-10-01T00:00:00Z