The Saccharomyces cerevisiae CDC6 gene is transcribed at late mitosis and encodes a ATP/GTPase controlling S phase initiation.
about
A human protein related to yeast Cdc6pCell cycle-regulated expression of mammalian CDC6 is dependent on E2F.The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeastCdc6 protein causes premature entry into S phase in a mammalian cell-free system.Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpointIdentification and characterization of a human protein kinase related to budding yeast Cdc7pIdentification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication.Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cellsPersistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutantsXenopus Cdc6 performs separate functions in initiating DNA replicationOrp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex.Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.Replication licensing--defining the proliferative state?The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin.Genetic and biochemical evaluation of the importance of Cdc6 in regulating mitotic exitCdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro.Roles of the CDK phosphorylation sites of yeast Cdc6 in chromatin binding and rereplication.Cdc6 degradation requires phosphodegron created by GSK-3 and Cdk1 for SCFCdc4 recognition in Saccharomyces cerevisiae.Inosine-5'-monophosphate dehydrogenase is a rate-determining factor for p53-dependent growth regulationInteraction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases.Mechanisms and regulation of DNA replication initiation in eukaryotes.Essential role of MCM proteins in premeiotic DNA replication.Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication.Adenovirus type 12-induced fragility of the human RNU2 locus requires U2 small nuclear RNA transcriptional regulatory elements.Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.The role and regulation of the preRC component Cdc6 in the initiation of premeiotic DNA replication.The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines.Mitotic Cdc6 stabilizes anaphase-promoting complex substrates by a partially Cdc28-independent mechanism, and this stabilization is suppressed by deletion of Cdc55Trypanosome prereplication machinery contains a single functional orc1/cdc6 protein, which is typical of archaea.Cdc18 transcription and proteolysis couple S phase to passage through mitosisYeast Num1p associates with the mother cell cortex during S/G2 phase and affects microtubular functions.The replication licensing system.The Replication Protein Cdc6 Suppresses Centrosome Over-Duplication in a Manner Independent of Its ATPase Activity.Expression and stability of Arabidopsis CDC6 are associated with endoreplication.
P2860
Q24312008-2DE0F2AD-A4F7-4E1F-B5A9-2AAA709D9036Q24522801-6FA93411-CEFA-446F-BAA1-F77A117404E6Q24532802-310380B2-2EE4-4A2B-A2EB-D50461DB50F5Q24533451-5F466BB5-18FC-4165-8D90-B4E210EF0D81Q24564395-751C7E35-223C-460F-B440-0178613B88C4Q24649005-69DB4E98-78C8-4817-9BD1-92399F2EC5BAQ24683693-81D9E924-DAC3-4B2F-BDE3-A3EA9E6D1BF3Q27939055-C395C6A2-5995-4F7D-99FC-38B78A6D3A20Q28348429-8737714B-F686-4450-A1E2-B19FAFDD9D9EQ28613373-E2F94F9E-90B3-4355-9311-C48CA446E5CAQ29614856-605EB120-BF3F-4E90-ADBB-26D06E6A8679Q33608362-CCA817B6-7E84-4C74-9CB7-B2874F434E48Q33683687-118F7134-D033-45BD-9C9A-99A9F6FE8C7FQ34010063-C2413096-B2DA-47A6-934D-EE130BE47CEDQ34534992-26C9F7AD-7F0B-4662-9204-6D5B60E95830Q34812174-677EABD1-C393-4271-A1DF-F2741F79144AQ35108200-4DB1F9D2-67B0-4F61-A538-1E7334965275Q35197268-573E6552-6DAB-4824-AEF6-38FEE63710DAQ35723519-7ECC5EA9-CC77-473E-A892-E665CDB26B0EQ35849098-6977617B-7772-4A28-A2B9-E8080F2B6971Q36847869-41508500-35DB-4BCF-8A1E-BD52EE939251Q37383225-9AC1620F-480C-4617-A794-7E21993656E4Q39017132-3E042E5A-18CA-440B-BB08-FD05B23C2E71Q39357471-7D9D0F08-3CE8-4901-A1D8-D8EF50EC4A51Q39645654-902385B5-40C0-4DB3-BCA1-7AC9F1F28E4EQ40017591-E47BB4D2-EA5E-4A62-9404-C3C8634F1DDDQ40789015-243AF24A-0062-40DC-963D-1EA670D44DAAQ40831416-2D36BDD2-B055-4088-A889-AE1145ADF6C5Q41461302-7BE6865A-3D68-4D36-8E9F-5C7B3F23A691Q42284590-A925DBD2-588F-4146-9139-A801DDD690BFQ42576404-034FE729-718E-4516-A569-8D4F5DD83134Q42655828-3904701B-FDBA-4F3D-A279-F8AA7F1A51EFQ42952999-3F028204-B228-43EC-A49B-14519E784A3BQ43221083-BEF61194-95DD-4517-87E2-D107350798BEQ47297306-17DDDD64-86D4-4F70-B31A-5328CAD7B668Q48327199-8B41B435-D9FE-4C5D-8147-6112A710CD24
P2860
The Saccharomyces cerevisiae CDC6 gene is transcribed at late mitosis and encodes a ATP/GTPase controlling S phase initiation.
description
1994 nî lūn-bûn
@nan
1994 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@ast
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@en
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@nl
type
label
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@ast
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@en
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@nl
prefLabel
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@ast
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@en
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@nl
P2093
P1476
The Saccharomyces cerevisiae C ...... ontrolling S phase initiation.
@en
P2093
H W Rottjakob
W Zwerschke
P304
P407
P577
1994-09-16T00:00:00Z