Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells
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Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cellsHuman SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaksIncreased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repairCENP-V is required for centromere organization, chromosome alignment and cytokinesis.The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cellsHinderin, a five-domains protein including coiled-coil motifs that binds to SMC3The constitutive centromere component CENP-50 is required for recovery from spindle damage.The chromosome cycle: coordinating replication and segregation. Second in the cycles review series.Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate.Kinetochore-microtubule interactions: steps towards bi-orientationShugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeresThe ancient and evolving roles of cohesin in gene expression and DNA repairCohesin is dispensable for centromere cohesion in human cellsSequential loading of cohesin subunits during the first meiotic prophase of grasshoppersCtf18 is required for homologous recombination-mediated double-strand break repairRecombination protein Tid1p controls resolution of cohesin-dependent linkages in meiosis in Saccharomyces cerevisiae.Double-strand breaks arising by replication through a nick are repaired by cohesin-dependent sister-chromatid exchange.In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin.Cohesin defects lead to premature sister chromatid separation, kinetochore dysfunction, and spindle-assembly checkpoint activationCohesin: functions beyond sister chromatid cohesionThe cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertilityDisruption of CHTF18 causes defective meiotic recombination in male miceSeparase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in miceA Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic ReprogrammingThe role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and mythsThe cellular geography of aurora kinasesCoordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance.Distinct developmental function of two Caenorhabditis elegans homologs of the cohesin subunit Scc1/Rad21.Studies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesionVariations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndromeNaa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion.Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data.Specific recruitment of human cohesin to laser-induced DNA damage.Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatinCentrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice.HCP-4/CENP-C promotes the prophase timing of centromere resolution by enabling the centromere association of HCP-6 in Caenorhabditis elegans."Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinasesCENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.Chiasmata promote monopolar attachment of sister chromatids and their co-segregation toward the proper pole during meiosis I.
P2860
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P2860
Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@ast
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@en
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@nl
type
label
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@ast
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@en
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@nl
prefLabel
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@ast
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@en
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@nl
P2093
P3181
P1433
P1476
Scc1/Rad21/Mcd1 is required fo ...... e function in vertebrate cells
@en
P2093
C Morrison
I C Waizenegger
J M Peters
P Vagnarelli
T Fukagawa
T Matsusaka
P304
P3181
P356
10.1016/S1534-5807(01)00088-0
P407
P577
2001-12-01T00:00:00Z