Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
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The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevisFbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich regionThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenancePhosphorylation of cyclin Y by CDK14 induces its ubiquitination and degradationRegulation of p27 degradation and S-phase progression by Ro52 RING finger proteinA growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.The stomatin-like protein SLP-1 and Cdk2 interact with the F-Box protein Fbw7-γFBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cellsThe glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7The ubiquitin-specific protease USP28 is required for MYC stabilityParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liverFAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activityUBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor geneM-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCPPhosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressorA dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapyThe ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.Phosphorylation of stem-loop binding protein (SLBP) on two threonines triggers degradation of SLBP, the sole cell cycle-regulated factor required for regulation of histone mRNA processing, at the end of S phaseSystematic analysis and nomenclature of mammalian F-box proteinsMicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7The ubiquitin proteasome system in neuropathologyFbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradationEndoreplication: polyploidy with purposeIsoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligasePhosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexA comprehensive pathway map of epidermal growth factor receptor signalingSCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysisTargeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesisReplication-initiator protein (UL9) of the herpes simplex virus 1 binds NFB42 and is degraded via the ubiquitin-proteasome pathwayBRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targetsCyclins in breast cancer: too much of a good thing.Low-molecular-weight cyclin E: the missing link between biology and clinical outcomeThe role of the ubiquitin proteasome system in cerebellar development and medulloblastomaEndoreplicationRegulation of Unperturbed DNA Replication by UbiquitylationMolecular functions of genes related to grain shape in riceTargeting the ubiquitin pathway for cancer treatment
P2860
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P2860
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@ast
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@en
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@nl
type
label
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@ast
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@en
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@nl
prefLabel
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@ast
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@en
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@nl
P2093
P3181
P356
P1433
P1476
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.1065203
P407
P577
2001-08-30T00:00:00Z