Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
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Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsRapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machineryCyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependencyBRCA1 is a negative modulator of the PRC2 complexSIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during agingPhosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNAInsulin-like growth factors and their potential role in cardiac epigeneticsIntegration of Signaling Pathways with the Epigenetic Machinery in the Maintenance of Stem CellsPolycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic ImplicationsPRC2 during vertebrate organogenesis: a complex in transitionPhosphorylation of epigenetic "readers, writers and erasers": Implications for developmental reprogramming and the epigenetic basis for health and diseaseProteomics in epigenetics: new perspectives for cancer researchStructural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2EZH2 in Bladder Cancer, a Promising Therapeutic TargetChromatin signaling in muscle stem cells: interpreting the regenerative microenvironmentDiverse involvement of EZH2 in cancer epigeneticsThe role of EZH2 in tumour progressionReactive oxygen species contribute to arsenic-induced EZH2 phosphorylation in human bronchial epithelial cells and lung cancer cellsJNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenicEpstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73αBreast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic changeWeaver Syndrome-Associated EZH2 Protein Variants Show Impaired Histone Methyltransferase Function In VitroThe polycomb repressive complex 2 is a potential target of SUMO modifications.Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7.NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes.EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia.Regulators of cellular levels of histone acetylation in Saccharomyces cerevisiaeA histone map of human chromosome 20q13.12.Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1.EZH2: not EZHY (easy) to deal.Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transitionComprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell linesReversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastomaMembrane-localized estrogen receptor α is required for normal organ development and function.MYC association with cancer risk and a new model of MYC-mediated repression.Histone modifications are associated with Δ9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responsesXenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT.
P2860
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P2860
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@ast
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@en
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@nl
type
label
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@ast
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@en
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@nl
prefLabel
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@ast
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@en
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@nl
P2093
P3181
P356
P1433
P1476
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3
@en
P2093
Arie P Otte
Binhua P Zhou
Cheng-Chieh Yang
Chun-Te Chen
Mien-Chie Hung
Tai-Lung Cha
P304
P3181
P356
10.1126/SCIENCE.1118947
P407
P577
2005-10-14T00:00:00Z