A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy - Test2 - elhamkhani - TriplyDB

A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

http://www.wikidata.org/entity/Q28391475

about

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients Proteostasis and Diseases of the Motor Unit.Shaping proteostasis at the cellular, tissue, and organismal level.Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.Safety and Efficacy of Nanocurcumin as Add-On Therapy to Riluzole in Patients With Amyotrophic Lateral Sclerosis: A Pilot Randomized Clinical Trial.Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

P2860

Q29247921-C1EDC543-D290-4D71-94BE-A603C7BC4D9F Q33614611-E12235EE-F57F-4F0A-A272-B31338D02A7A Q39084550-80137DAF-FE87-4614-AFFC-F7F3C6FDC47E Q39235911-35313116-202C-41D0-88D5-1570F6DD1BF2 Q41575678-AC3D63C8-1E26-4B48-8D73-C8ADB6A0F596 Q47722450-EEEA1C88-95DF-44AD-AC2F-09DA935019B5 Q52674189-DAB67DF1-F156-4BD7-8820-8D6BEBB5F0FA

P2860

A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

http://www.wikidata.org/entity/Q28391475

description

2016 nî lūn-bûn

@nan

2016 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@ast

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@en

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@nl

type

label

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@ast

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@en

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@nl

prefLabel

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@ast

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@en

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@nl

P1433

Q28391475-98D15238-B5F0-4D04-BF9D-D527031DD57F

P1476

Q28391475-BF26E1AF-B0A3-4B37-BC7B-E949B921EE0B

P2093

Q28391475-26FCE024-8728-4A68-8BD3-005BD66D0084

Q28391475-2A60ECA1-F416-46E2-8B1C-69EF5F4E4EDA

Q28391475-308ADB2E-FDE9-481F-899B-B17E370779EA

Q28391475-5780636F-B0DA-4822-AE18-94B2E3A3CDDC

Q28391475-5A3E0725-B7DC-46E5-AAB7-6A5CA1F7339B

Q28391475-9E3D5B47-0156-4AB9-AB19-669C4AB91B03

Q28391475-9F34D8FB-5BF2-49EE-9D95-D8680C3A4B71

Q28391475-AC9B22D2-FBF5-40BE-A198-117705967C6D

Q28391475-B91C80C9-62B1-40DB-B454-85A0D25E33B4

P2860

Q28391475-0245829E-AEE5-43C1-B16D-7A6349962DD1

Q28391475-087BC344-FA78-45F8-9AF2-2143CFE506E3

Q28391475-0E86AD27-3EBE-41E8-84A7-691A2019F456

Q28391475-130BBDB2-59B6-45DA-914D-BED7FE444EB2

Q28391475-214BCB34-22FE-4253-AE8F-BF6259A64E1C

Q28391475-35A5F537-AF8A-4FBF-8595-D8D2A9920102

Q28391475-453E6631-85D5-40A6-854F-049C27279733

Q28391475-457A5CE6-D433-4D5A-8638-160FAE4B7F3A

Q28391475-46643161-F2EF-4724-8B55-261F6D666DAE

Q28391475-483E23A0-608F-407F-8AB5-ABA856D30C22

P304

Q28391475-9E2A23FC-69A8-49EE-BD3F-F576EA212324

P31

Q28391475-05CA39C4-52AD-49EE-A078-1FC231C1D5FF

P3181

Q28391475-C9874E04-0800-4A35-A380-4AC4F8A4DC13

P356

Q28391475-CE818611-6F5E-4C1F-B44C-31CAA3ECBCA7

P407

Q28391475-D5D82075-987D-46EC-A10B-ED282585ED4B

P433

Q28391475-68554210-7D15-42C9-BCA7-72C452A252B1

P478

Q28391475-A734B8F0-4FC9-45B1-BE03-E712061C3583

P50

Q28391475-78CBA880-C66A-4EB9-9C10-BBD56CD4251E

Q28391475-8EABFA42-12C9-4D5B-B189-517AC8E1BDA8

Q28391475-DA37A7A2-35BE-465D-AC07-AA121765DDBF

P577

Q28391475-1B50BAE6-43D0-49FC-B699-CA46092B2583

P698

Q28391475-71DC30BB-113E-451A-BB24-9B45EAB71697

P932

Q28391475-1C44F469-C358-47D9-8027-46D1975448AD

P3181

P356

P1433

Human Molecular Genetics

P1476

A small-molecule Nrf1 and Nrf2 ...... al and bulbar muscular atrophy

@en

P2093

Carlo Rinaldi

http://www.w3.org/2001/XMLSchema#string

Charles C-Y Shih

http://www.w3.org/2001/XMLSchema#string

Elaine Bautista

http://www.w3.org/2001/XMLSchema#string

George G Harmison

http://www.w3.org/2001/XMLSchema#string

Ke-Lian Chen

http://www.w3.org/2001/XMLSchema#string

Kenneth H Fischbeck

http://www.w3.org/2001/XMLSchema#string

Laura C Bott

http://www.w3.org/2001/XMLSchema#string

Masahisa Katsuno

http://www.w3.org/2001/XMLSchema#string

Nisha M Badders

http://www.w3.org/2001/XMLSchema#string

P2860

Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2

Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice.

Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases

Curcumin as a therapeutic agent in dementia: a mini systematic review of human studies

Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin

The ubiquitin system

Adapting proteostasis for disease intervention

Proteasome-mediated processing of Nrf1 is essential for coordinate induction of all proteasome subunits and p97

Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum

Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells

P304

1979-1989

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4518170

http://www.w3.org/2001/XMLSchema#string

P356

10.1093/HMG/DDW073

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

25

http://www.w3.org/2001/XMLSchema#string

P50

Nico P. Dantuma

P577

2016-05-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26962150

http://www.w3.org/2001/XMLSchema#string

P932

5062587

http://www.w3.org/2001/XMLSchema#string