Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members - Test2 - elhamkhani - TriplyDB

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

http://www.wikidata.org/entity/Q28504488

about

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide APLP2 Regulates Refractive Error and Myopia Development in Mice and Humans Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cells Homo- and heterodimerization of APP family members promotes intercellular adhesion.The amyloid-beta precursor protein: integrating structure with biological function Interaction of reelin with amyloid precursor protein promotes neurite outgrowth Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 The amyloid precursor protein: beyond amyloid Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis Amyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta pores Amyloid Proteins and Their Role in Multiple Sclerosis. Considerations in the Use of Amyloid-PET Imaging Caenorhabditis elegans as a model organism to study APP function Proteoglycans in the central nervous system: role in development, neural repair, and Alzheimer's disease Tailoring the antibody response to aggregated Aß using novel Alzheimer-vaccines Structural Characterization of the E2 Domain of APL-1, a Caenorhabditis elegans Homolog of Human Amyloid Precursor Protein, and Its Heparin Binding Site The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization APP processing in Alzheimer's disease Role of Drosophila Amyloid Precursor Protein in Memory Formation Dynamic self-guiding analysis of Alzheimer's disease.Proteolytic processing of Alzheimer's β-amyloid precursor protein DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage The in vivo brain interactome of the amyloid precursor protein APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functions Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks Amyloid precursor protein trafficking, processing, and function Truncating mutations in APP cause a distinct neurological phenotype.Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification.Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers.A framework for modeling the growth and development of neurons and networks.Alzheimer disease models and human neuropathology: similarities and differences How to innervate a simple gut: familiar themes and unique aspects in the formation of the insect enteric nervous system.FoxO mediates APP-induced AICD-dependent cell death.Impaired structural correlates of memory in Alzheimer's disease mice.Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression.

P2860

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P248

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P2860

Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

http://www.wikidata.org/entity/Q28504488

description

2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2004

@ast

im Oktober 2004 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2004/10/13)

@sk

vědecký článek publikovaný v roce 2004

@cs

wetenschappelijk artikel (gepubliceerd op 2004/10/13)

@nl

наукова стаття, опублікована в жовтні 2004

@uk

مقالة علمية (نشرت في 13-10-2004)

@ar

name

Cortical dysplasia resembling ...... g all three APP family members

@ast

Cortical dysplasia resembling ...... g all three APP family members

@en

Cortical dysplasia resembling ...... g all three APP family members

@nl

type

label

Cortical dysplasia resembling ...... g all three APP family members

@ast

Cortical dysplasia resembling ...... g all three APP family members

@en

Cortical dysplasia resembling ...... g all three APP family members

@nl

prefLabel

Cortical dysplasia resembling ...... g all three APP family members

@ast

Cortical dysplasia resembling ...... g all three APP family members

@en

Cortical dysplasia resembling ...... g all three APP family members

@nl

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P3181

P356

SJ.EMBOJ.7600390

P1433

The EMBO Journal

P1476

Cortical dysplasia resembling ...... g all three APP family members

@en

P2093

Brigitte Anliker

http://www.w3.org/2001/XMLSchema#string

Hans Kretzschmar

http://www.w3.org/2001/XMLSchema#string

Jochen Herms

http://www.w3.org/2001/XMLSchema#string

Martin Fuhrmann

http://www.w3.org/2001/XMLSchema#string

Sabine Heber

http://www.w3.org/2001/XMLSchema#string

Sabine Ring

http://www.w3.org/2001/XMLSchema#string

Sangram Sisodia

http://www.w3.org/2001/XMLSchema#string

Ulrike Müller

http://www.w3.org/2001/XMLSchema#string

P2860

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1

Proteolytic processing and cell biological functions of the amyloid precursor protein

Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

Reelin and brain development

gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins

Role of the reelin signaling pathway in central nervous system development

Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation

P304

4106–4115

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scholarly article

P3181

3844818

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P356

10.1038/SJ.EMBOJ.7600390

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P407

P433

20

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23

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P577

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8328959

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P698

15385965

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P921

Amyloid beta (A4) precursor protein

Amyloid beta (A4) precursor-like protein 1

Amyloid beta (A4) precursor-like protein 2

P932

524337

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