Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein
about
The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptideDisruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of the corpus callosumInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseHippocampal network oscillations in APP/APLP2-deficient miceThe K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosumCortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family membersEssential roles for the FE65 amyloid precursor protein-interacting proteins in brain developmentTruncating mutations in APP cause a distinct neurological phenotype.Differences in memory development among C57BL/6NCrl, 129S2/SvPasCrl, and FVB/NCrl mice after delay and trace fear conditioning.COL25A1 triggers and promotes Alzheimer's disease-like pathology in vivo.Alzheimer disease models and human neuropathology: similarities and differencesNeuronal untranslated BC1 RNA: targeted gene elimination in mice.Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression.Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortexFunction, therapeutic potential and cell biology of BACE proteases: current status and future prospects.Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis.Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation.The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.Finding the most appropriate mouse model of juvenile CLN3 (Batten) disease for therapeutic studies: the importance of genetic background and gender.Deficits in axonal transport in hippocampal-based circuitry and the visual pathway in APP knock-out animals witnessed by manganese enhanced MRI.Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice.All in the Family: How the APPs Regulate NeurogenesisAmyloid precursor protein regulates netrin-1-mediated commissural axon outgrowthThe protection of acetylcholinesterase inhibitor on β-amyloid-induced the injury of neurite outgrowth via regulating axon guidance related genes expression in neuronal cells.Hippocampal commissure defects in crosses of four inbred mouse strains with absent corpus callosum.Loss of presenilin function is associated with a selective gain of APP function.Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis.Understanding the molecular basis of Alzheimer's disease using a Caenorhabditis elegans model system.Amyloid-modifying therapies for Alzheimer's disease: therapeutic progress and its implications.Biology and pathophysiology of the amyloid precursor protein.Functions of the APP gene family in the nervous system: insights from mouse models.The gene or not the gene--that is the question: understanding the genetically engineered mouse phenotype.Physiological functions of APP family proteins.Similar reliability and equivalent performance of female and male mice in the open field and water-maze place navigation taskExpression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic miceThe Role of APP in Structural Spine Plasticity.Not just amyloid: physiological functions of the amyloid precursor protein family.GABAergic hyperinnervation of dentate granule cells in the Ts65Dn mouse model of down syndrome: Exploring the role of App.The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system.Transcriptomic profile analysis of mouse neural tube development by RNA-Seq.
P2860
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P2860
Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein
description
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1999
@ast
im April 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/04/13)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/04/13)
@nl
наукова стаття, опублікована у квітні 1999
@uk
name
Genetic background changes the ...... beta-amyloid-precursor protein
@ast
Genetic background changes the ...... beta-amyloid-precursor protein
@en
Genetic background changes the ...... beta-amyloid-precursor protein
@nl
type
label
Genetic background changes the ...... beta-amyloid-precursor protein
@ast
Genetic background changes the ...... beta-amyloid-precursor protein
@en
Genetic background changes the ...... beta-amyloid-precursor protein
@nl
prefLabel
Genetic background changes the ...... beta-amyloid-precursor protein
@ast
Genetic background changes the ...... beta-amyloid-precursor protein
@en
Genetic background changes the ...... beta-amyloid-precursor protein
@nl
P2093
P2860
P3181
P356
P1476
Genetic background changes the ...... beta-amyloid-precursor protein
@en
P2093
C. Weissmann
D. P. Wolfer
H. P. Lipp
M. Stagljar
P2860
P304
P3181
P356
10.1073/PNAS.96.8.4656
P407
P577
1999-04-13T00:00:00Z