SCL and associated proteins distinguish active from repressive GATA transcription factor complexes - Test2 - elhamkhani - TriplyDB

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

http://www.wikidata.org/entity/Q28591576

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A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1 Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications Transcription factors in late megakaryopoiesis and related platelet disorders Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1 Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies Functions of BET proteins in erythroid gene expression Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor Analysis of disease-causing GATA1 mutations in murine gene complementation systems Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.BMP-mediated specification of the erythroid lineage suppresses endothelial development in blood island precursors Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation.FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment.Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci Role of LDB1 in the transition from chromatin looping to transcription activation.Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes.Reactivation of developmentally silenced globin genes by forced chromatin looping.Lineage-specific combinatorial action of enhancers regulates mouse erythroid Gata1 expression Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1.A requirement for Lim domain binding protein 1 in erythropoiesis.Transcriptional activation of prostate specific homeobox gene NKX3-1 in subsets of T-cell lymphoblastic leukemia (T-ALL).Building multifunctionality into a complex containing master regulators of hematopoiesis.3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation.Regulation of delta-aminolevulinic acid dehydratase by krüppel-like factor 1.Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.Dynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiation Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.Transcription factor networks in erythroid cell and megakaryocyte development

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P2860

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

http://www.wikidata.org/entity/Q28591576

description

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մարտին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2009

@ast

im März 2009 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2009/03/05)

@sk

vědecký článek publikovaný v roce 2009

@cs

wetenschappelijk artikel (gepubliceerd op 2009/03/05)

@nl

наукова стаття, опублікована в березні 2009

@uk

مقالة علمية (نشرت في 5-3-2009)

@ar

name

SCL and associated proteins di ...... transcription factor complexes

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SCL and associated proteins di ...... transcription factor complexes

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SCL and associated proteins di ...... transcription factor complexes

@nl

type

label

SCL and associated proteins di ...... transcription factor complexes

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SCL and associated proteins di ...... transcription factor complexes

@en

SCL and associated proteins di ...... transcription factor complexes

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prefLabel

SCL and associated proteins di ...... transcription factor complexes

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SCL and associated proteins di ...... transcription factor complexes

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SCL and associated proteins di ...... transcription factor complexes

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SCL and associated proteins di ...... transcription factor complexes

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Gerd A Blobel

http://www.w3.org/2001/XMLSchema#string

Gregory D Gregory

http://www.w3.org/2001/XMLSchema#string

Tamara Tripic

http://www.w3.org/2001/XMLSchema#string

Wulan Deng

http://www.w3.org/2001/XMLSchema#string

Yong Cheng

http://www.w3.org/2001/XMLSchema#string

P2860

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

GATA-1 forms distinct activating and repressive complexes in erythroid cells

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1

TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

ETO2 coordinates cellular proliferation and differentiation during erythropoiesis

Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein

Transcriptional regulation of erythropoiesis: an affair involving multiple partners

P304

2191-2201

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scholarly article

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2817599

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10.1182/BLOOD-2008-07-169417

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10

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Christopher R. Vakoc

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2008-11-14T00:00:00Z

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23475554

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T cell acute lymphocytic leukemia 1

GATA binding protein 1

Transcription factor 3

LIM domain only 2

LIM domain binding 1

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2652367

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