Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization - Test2 - elhamkhani - TriplyDB

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

http://www.wikidata.org/entity/Q29615622

about

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1 High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy Hexokinase activity is required for recruitment of parkin to depolarized mitochondria Chaperone-Mediated Autophagy and Mitochondrial Homeostasis in Parkinson's Disease Metabolic, autophagic, and mitophagic activities in cancer initiation and progression Cullin-RING ligases in regulation of autophagy DUBs, New Members in the Hypoxia Signaling clUb Myosins, Actin and Autophagy Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease Metabolic regulation of mitochondrial dynamics Alterations in Mitochondrial Quality Control in Alzheimer's Disease Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy The Function of Autophagy in Neurodegenerative Diseases A Mechanistic Review of Mitophagy and Its Role in Protection against Alcoholic Liver Disease Autophagy signal transduction by ATG proteins: from hierarchies to networks Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?Expanding the ubiquitin code through post-translational modification Quantifying ubiquitin signaling RBR E3 ubiquitin ligases: new structures, new insights, new questions The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease Parkin structure and function Recent advances in quantitative neuroproteomics Mitoconfusion: noncanonical functioning of dynamism factors in static mitochondria of the heart Emerging strategies to effectively target autophagy in cancer Mitochondrial quality control: decommissioning power plants in neurodegenerative diseases Pathologic and therapeutic implications for the cell biology of parkin Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection Quality control in mitochondria: use it, break it, fix it, trash it Self and nonself: how autophagy targets mitochondria and bacteria Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin Activation of the E3 ubiquitin ligase Parkin.Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease

P2860

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P2860

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

http://www.wikidata.org/entity/Q29615622

description

2013 nî lūn-bûn

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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

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2013年論文

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2013年论文

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name

Landscape of the PARKIN-depend ...... o mitochondrial depolarization

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Landscape of the PARKIN-depend ...... o mitochondrial depolarization

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type

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Landscape of the PARKIN-depend ...... o mitochondrial depolarization

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Landscape of the PARKIN-depend ...... o mitochondrial depolarization

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prefLabel

Landscape of the PARKIN-depend ...... o mitochondrial depolarization

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Landscape of the PARKIN-depend ...... o mitochondrial depolarization

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Landscape of the PARKIN-depend ...... o mitochondrial depolarization

@en

P2093

Mathew E Sowa

http://www.w3.org/2001/XMLSchema#string

Shireen A Sarraf

http://www.w3.org/2001/XMLSchema#string

Virginia Guarani-Pereira

http://www.w3.org/2001/XMLSchema#string

P2860

Control of mitochondrial morphology through differential interactions of mitochondrial fusion and fission proteins

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

Autoregulation of Parkin activity through its ubiquitin-like domain

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling

Defining the human deubiquitinating enzyme interaction landscape

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372-376

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scholarly article

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469680

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10.1038/NATURE12043

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7445

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496

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Jeffrey W. Harper

Edward L Huttlin

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2013-03-17T00:00:00Z

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236056194

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1001357065

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23503661

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3641819

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