BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
about
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replicationHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repairThe RecQ DNA helicases in DNA repairHomologous recombination in DNA repair and DNA damage toleranceHuman RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biologyRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingMore complexity to the Bloom's syndrome complexRMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityBLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasomeRECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filamentsMus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiaeFunctions and regulation of the multitasking FANCM family of DNA motor proteinsSmc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisionsStructure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome DissolvasomeDefining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasomeStructural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1RecQ helicases in DNA double strand break repair and telomere maintenance.Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.Rmi1, a member of the Sgs1-Top3 complex in budding yeast, contributes to sister chromatid cohesionDecatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae.Identification of nucleases and phosphatases by direct biochemical screen of the Saccharomyces cerevisiae proteome.Binding and activation of DNA topoisomerase III by the Rmi1 subunit.RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination.Mus81/Mms4 endonuclease and Sgs1 helicase collaborate to ensure proper recombination intermediate metabolism during meiosis.Multiple mechanisms limit meiotic crossovers: TOP3α and two BLM homologs antagonize crossovers in parallel to FANCMHuman exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repairThe broken genome: genetic and pharmacologic approaches to breaking DNATopoisomerase 3alpha and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thalianaRMI1 deficiency in mice protects from diet and genetic-induced obesityLoss of RMI2 Increases Genome Instability and Causes a Bloom-Like SyndromeETAA1 acts at stalled replication forks to maintain genome integrityThe evolutionary origin of man can be traced in the layers of defunct ancestral alpha satellites flanking the active centromeres of human chromosomesAdipocyte hyperplasia and RMI1 in the treatment of obesity.Novel pro- and anti-recombination activities of the Bloom's syndrome helicase.Topoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres.TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeresSUMO modification regulates BLM and RAD51 interaction at damaged replication forks.Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes
P2860
Q24295460-0FB524D9-0CA7-45A1-AA48-5C0FE8086298Q24310243-EC8A63E1-EEAD-4FAA-AC41-4B94A9769E9EQ24336963-2EAF59A6-DA58-42C6-B92E-0F20333B316EQ24561510-A69EC515-609D-4332-B94F-CD678367DFDCQ24601150-F233C7C9-8B58-4807-8F23-18758ADA75CFQ24620195-E883F092-94FB-490C-BCC1-8B1DBA3D9700Q24646853-D260CA74-3126-4F70-B51F-10F662F2371DQ24647810-54AEF8B7-4FE7-45C4-9E41-A11AC68948F4Q24650860-4CF48CBD-D35F-453F-8D7D-1A755C92767EQ24650899-B306E0BF-7B23-4883-B94C-FFEAC4CAABF3Q24676019-B99580C7-6128-40D8-816C-A2457BD2465EQ24684096-BE9EF933-D4CF-4869-ADA2-D7B4B57CF06EQ26784076-AFB00E45-9692-4A13-BB06-73D7A73A90FBQ27317410-440E9D2E-8AAA-4204-921D-701E335630C6Q27664369-B8263896-3290-4544-B250-FB0713E1C1E2Q27677852-7DC4437F-EB49-48CD-B87D-C80671DDEB66Q27681649-747B73CC-518A-4ABC-B28B-FD508D7D7350Q27692685-635D2EAB-36D9-4D12-B042-BA8ABAF5AB5FQ27929966-300FBE6B-7803-4655-B7E6-326006586C60Q27932711-0474EF62-E594-42F1-BA2D-021E0AD59F5CQ27937337-60F7D47F-76EE-48D4-A66E-F6AF89F89860Q27937523-209F7C05-83F8-4A6F-A3A4-138D527B3EA7Q27938092-73D4B585-A94B-4723-9F3C-162B7CC81BBDQ27938793-38D7036B-A009-41E9-9B21-609E932021CBQ27939265-2C73599B-9E3D-4B8A-96E6-4328B96AD2D8Q27940287-25F5E333-0CE1-45C3-8F1C-2EFCB5A82FC4Q28259690-62A64F95-2A9B-4917-9EFA-E31DCB8FA905Q28299185-C61FCA54-0962-4A2C-9DBA-721461EEB998Q28299327-A79BDDB0-9369-42A0-A1EE-BCA58EC6A50DQ28474239-6A7CA216-648D-45DF-ADC1-4A0E41B57BDDQ28592051-EE9110EC-D4A7-40A1-AC20-E96F2472679CQ28596601-14FE30F8-F23E-41E3-B24A-DEC2CDE7007DQ28596606-B47BB886-6912-440D-A8F0-F24B8BDF2BCDQ28751890-0CBE86CA-E452-4C0A-A5C3-3C490411A5CDQ30398044-68C71489-6929-4EEE-BF19-7B5177604817Q30441651-8142E122-9022-42F5-B846-57866C4833C3Q30482066-80F9E4EE-C02D-461C-B020-08DBDE1871ADQ30580233-DF4D6FF8-A8EA-4507-8682-E3AF20B77318Q30940899-A7E80324-24AB-4603-89F4-3E8202184973Q31814838-E081D0AE-6D98-47F9-9D5B-319ACC3D8EE9
P2860
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@ast
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@en
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@nl
type
label
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@ast
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@en
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@nl
prefLabel
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@ast
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@en
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@nl
P2093
P2860
P50
P3181
P356
P1476
BLAP75/RMI1 promotes the BLM-d ...... us recombination intermediates
@en
P2093
Ian D Hickson
Jiongwen Ou
Leonard Wu
Weidong Wang
P2860
P304
P3181
P356
10.1073/PNAS.0508295103
P407
P577
2006-03-14T00:00:00Z