RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination
about
Different quaternary structures of human RECQ1 are associated with its dual enzymatic activityPhysical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factorsThe hSNM1 protein is a DNA 5'-exonucleaseHuman premature aging, DNA repair and RecQ helicasesMultiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNAStructures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease FamilyMechanisms and functions of DNA mismatch repairHuman RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges.Distinct roles of RECQ1 in the maintenance of genomic stability.Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks.Delineation of WRN helicase function with EXO1 in the replicational stress responseBiochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1.Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer.Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structuresSignificant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival.Human RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaksRECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers.Mismatch repair during homologous and homeologous recombinationDNA mismatch repair network gene polymorphism as a susceptibility factor for pancreatic cancerMutations in RECQL Gene Are Associated with Predisposition to Breast CancerDNA mismatch repair gene polymorphisms affect survival in pancreatic cancer.RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast geneticsDNA helicases involved in DNA repair and their roles in cancer14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif.Human RecQ helicases in DNA repair, recombination, and replication.RECQ1 plays a distinct role in cellular response to oxidative DNA damage.Human exonuclease 1 (EXO1) activity characterization and its function on flap structures.Repeat instability: mechanisms of dynamic mutations.ATR-dependent pathways control hEXO1 stability in response to stalled forks.Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stabilityUnique and important consequences of RECQ1 deficiency in mammalian cells.RECQ1 possesses DNA branch migration activity.RECQL: a new breast cancer susceptibility gene.RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704.The BLM dissolvasome in DNA replication and repair.Significant associations of mismatch repair gene polymorphisms with clinical outcome of pancreatic cancer.Hitting the bull's eye: novel directed cancer therapy through helicase-targeted synthetic lethality.Single nucleotide polymorphism in RECQL and survival in resectable pancreatic adenocarcinoma.
P2860
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P2860
RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
RECQ1 helicase interacts with ...... regulate genetic recombination
@ast
RECQ1 helicase interacts with ...... regulate genetic recombination
@en
RECQ1 helicase interacts with ...... regulate genetic recombination
@en-gb
RECQ1 helicase interacts with ...... regulate genetic recombination
@nl
type
label
RECQ1 helicase interacts with ...... regulate genetic recombination
@ast
RECQ1 helicase interacts with ...... regulate genetic recombination
@en
RECQ1 helicase interacts with ...... regulate genetic recombination
@en-gb
RECQ1 helicase interacts with ...... regulate genetic recombination
@nl
prefLabel
RECQ1 helicase interacts with ...... regulate genetic recombination
@ast
RECQ1 helicase interacts with ...... regulate genetic recombination
@en
RECQ1 helicase interacts with ...... regulate genetic recombination
@en-gb
RECQ1 helicase interacts with ...... regulate genetic recombination
@nl
P2093
P2860
P356
P1476
RECQ1 helicase interacts with ...... regulate genetic recombination
@en
P2093
Alessandro Vindigni
Kevin M Doherty
Laura A Uzdilla
Robert M Brosh
Teresa M Wilson
P2860
P304
28085-28094
P356
10.1074/JBC.M500265200
P407
P577
2005-05-09T00:00:00Z