Identification of N-terminal lobe motifs that determine the kinase activity of the catalytic domains and regulatory strategies of Src and Csk protein tyrosine kinases.
about
Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation.Distal loop flexibility of a regulatory domain modulates dynamics and activity of C-terminal SRC kinase (csk)T-cell signaling regulated by the Tec family kinase, Itk.Identification of an allosteric signaling network within Tec family kinases.Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic AnalysisCyclic peptides containing tryptophan and arginine as Src kinase inhibitors.Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin.Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases.Design, Synthesis, and Evaluation of Dasatinib-Amino Acid and Dasatinib-Fatty Acid Conjugates as Protein Tyrosine Kinase Inhibitors.Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms.Optogenetically controlled protein kinases for regulation of cellular signaling.Csk-homologous kinase (Chk/Matk): a molecular policeman suppressing cancer formation and progression
P2860
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P2860
Identification of N-terminal lobe motifs that determine the kinase activity of the catalytic domains and regulatory strategies of Src and Csk protein tyrosine kinases.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of N-terminal l ...... Csk protein tyrosine kinases.
@ast
Identification of N-terminal l ...... Csk protein tyrosine kinases.
@en
type
label
Identification of N-terminal l ...... Csk protein tyrosine kinases.
@ast
Identification of N-terminal l ...... Csk protein tyrosine kinases.
@en
prefLabel
Identification of N-terminal l ...... Csk protein tyrosine kinases.
@ast
Identification of N-terminal l ...... Csk protein tyrosine kinases.
@en
P2093
P2860
P1476
Identification of N-terminal l ...... d Csk protein tyrosine kinases
@en
P2093
Gongqin Sun
Kezhen Huang
Yue-Hao Wang
P2860
P304
P356
10.1016/J.JMB.2009.01.012
P407
P50
P577
2009-03-01T00:00:00Z