Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit.
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Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neuronsPrefrontal Cortex and Social Cognition in Mouse and ManAltered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouseNeurobiology of social behavior abnormalities in autism and Williams syndromeIntegrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations.Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism.Brain Injury Impairs Working Memory and Prefrontal Circuit Function.Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disordersMonogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder.Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders.Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders.Behavioural Phenotypes and Neural Circuit Dysfunctions in Mouse Models of Autism Spectrum Disorder.Reelin-Haploinsufficiency Disrupts the Developmental Trajectory of the E/I Balance in the Prefrontal Cortex.Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations.Drd3 Signaling in the Lateral Septum Mediates Early Life Stress-Induced Social Dysfunction.Inhibitory control of the excitatory/inhibitory balance in psychiatric disorders.Shank3-deficient thalamocortical neurons show HCN channelopathy and alterations in intrinsic electrical properties.Excitatory and inhibitory synaptic dysfunction in mania: an emerging hypothesis from animal model studies.CRISPR/Cas9-induced shank3b mutant zebrafish display autism-like behaviors.Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors.Impaired Hippocampal Synaptic Plasticity and Enhanced Excitatory Transmission in a Novel Animal Model of Autism Spectrum Disorders with Telomerase Reverse Transcriptase Overexpression.Distinct Phenotypes of Mouse Models Reflect Neuropsychiatric Spectrum Disorders of Human Patients With VariantsBehavioral Phenotyping of an Improved Mouse Model of Phelan-McDermid Syndrome with a Complete Deletion of the GeneIntegrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in -Overexpressing MiceGABA Neuronal Deletion of Exons 14-16 in Mice Suppresses Striatal Excitatory Synaptic Input and Induces Social and Locomotor AbnormalitiesToward the Language OscillogenomePotentiation of Glutamatergic Synaptic Transmission Onto Dorsal Raphe Serotonergic Neurons in the Valproic Acid Model of Autism
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P2860
Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit.
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Shank3-mutant mice lacking exo ...... g, and spatial memory deficit.
@ast
Shank3-mutant mice lacking exo ...... g, and spatial memory deficit.
@en
type
label
Shank3-mutant mice lacking exo ...... g, and spatial memory deficit.
@ast
Shank3-mutant mice lacking exo ...... g, and spatial memory deficit.
@en
prefLabel
Shank3-mutant mice lacking exo ...... g, and spatial memory deficit.
@ast
Shank3-mutant mice lacking exo ...... g, and spatial memory deficit.
@en
P2093
P2860
P356
P1476
Shank3-mutant mice lacking exo ...... g, and spatial memory deficit.
@en
P2093
Changuk Chung
Do-Young Kim
Dongmin Lee
Eunjoon Kim
Jiseok Lee
Seungmin Ha
P2860
P356
10.3389/FNCEL.2015.00094
P577
2015-03-19T00:00:00Z