Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line.
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Structure of Human Prostasin, a Target for the Regulation of HypertensionActive site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cationsProstasin regulates epithelial monolayer function: cell-specific Gpld1-mediated secretion and functional role for GPI anchor.Membrane-anchored serine proteases in vertebrate cell and developmental biologyPurinergic receptors in airway epithelia.Urinary prostasin in humans: relationships among prostasin, aldosterone and epithelial sodium channel activity.Intracellular Na+ regulates epithelial Na+ channel maturation.Prostasin: An Epithelial Sodium Channel Regulator.Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic ProteasesActivity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cellsSoluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.Effective mucus clearance is essential for respiratory health.Endogenous protease activation of ENaC: effect of serine protease inhibition on ENaC single channel properties.Hypermethylation of the 5' CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis.Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis.Regulation of the epithelial Na+ channel by peptidases.Liquid movement across the surface epithelium of large airwaysThe cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.A matriptase-prostasin reciprocal zymogen activation complex with unique features: prostasin as a non-enzymatic co-factor for matriptase activation.Membrane-anchored serine proteases in health and disease.Reduced sodium transport with nasal administration of the prostasin inhibitor camostat in subjects with cystic fibrosis.Methodology and applications of disease biomarker identification in human serum.Expression of prostasin and protease nexin-1 in rhesus monkey (Macaca mulatta) endometrium and placenta during early pregnancy.Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.The matriptase-prostasin proteolytic cascade in epithelial development and pathology.Proteases, cystic fibrosis and the epithelial sodium channel (ENaC).Water Permeability Adjusts Resorption in Lung Epithelia to Increased Apical Surface Liquid Volumes.Strong expression association between matriptase and its substrate prostasin in breast cancer.Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na⁺ transport in response to apical fluid volume expansion in human H441 airway epithelial cells.Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells.Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.The guinea-pig tracheal potential difference as an in vivo model for the study of epithelial sodium channel function in the airways.Acute regulation of the epithelial sodium channel in airway epithelia by proteases and trafficking.ENaC proteolytic regulation by channel-activating protease 2.Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis.Cathepsin B contributes to Na+ hyperabsorption in cystic fibrosis airway epithelial cultures.
P2860
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P2860
Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line.
description
2004 nî lūn-bûn
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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@ast
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@en
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@nl
type
label
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@ast
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@en
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@nl
prefLabel
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@ast
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@en
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@nl
P2093
P2860
P1476
Prostasin, a membrane-anchored ...... s airway epithelial cell line.
@en
P2093
Beate Illek
George H Caughey
George M Verghese
Vikash J Bhagwandin
Zhenyue Tong
P2860
P304
P356
10.1152/AJPLUNG.00160.2004
P577
2004-07-09T00:00:00Z