A multiplasmid approach to preparing large libraries of polyketides.
about
Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donorImportance of microbial natural products and the need to revitalize their discovery.Diversity of polyketide synthase genes from bacteria associated with the marine sponge Pseudoceratina clavata: culture-dependent and culture-independent approaches.Engineered production of iso-migrastatin in heterologous Streptomyces hosts.Biosynthesis of polyketides in heterologous hostsEngineered polyketide biosynthesis and biocatalysis in Escherichia coli.Artificial chromosomes to explore and to exploit biosynthetic capabilities of actinomycetes.The enzymology of combinatorial biosynthesis.Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis.Combinatorial biosynthesis of reduced polyketides.The type I fatty acid and polyketide synthases: a tale of two megasynthasesPolyketide chain skipping mechanism in the biosynthesis of the hybrid nonribosomal peptide-polyketide antitumor antibiotic leinamycin in Streptomyces atroolivaceus S-140.Recombinant organisms for production of industrial products.The structures of type I polyketide synthases.Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis.The role of transcription in heterologous expression of polyketides in bacterial hosts.Dissecting complex polyketide biosynthesis.Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects.Probing the influence of an allylic methyl group in zearalenone analogues on binding to Hsp90.Heterologous expression and manipulation of three tetracycline biosynthetic pathways.Rapid engineering of the geldanamycin biosynthesis pathway by Red/ET recombination and gene complementationCharacterization of a large, stable, high-copy-number Streptomyces plasmid that requires stability and transfer functions for heterologous polyketide overproduction.Modification of rifamycin polyketide backbone leads to improved drug activity against rifampicin-resistant Mycobacterium tuberculosis.Sequence, cloning, and analysis of the fluvirucin B1 polyketide synthase from Actinomadura vulgaris.Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions.A mechanism-based fluorescence transfer assay for examining ketosynthase selectivity.A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst.Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.Broad substrate specificity of ketoreductases derived from modular polyketide synthases.Discovery of the leinamycin family of natural products by mining actinobacterial genomes.Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides.
P2860
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P2860
A multiplasmid approach to preparing large libraries of polyketides.
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A multiplasmid approach to preparing large libraries of polyketides.
@ast
A multiplasmid approach to preparing large libraries of polyketides.
@en
type
label
A multiplasmid approach to preparing large libraries of polyketides.
@ast
A multiplasmid approach to preparing large libraries of polyketides.
@en
prefLabel
A multiplasmid approach to preparing large libraries of polyketides.
@ast
A multiplasmid approach to preparing large libraries of polyketides.
@en
P2093
P2860
P356
P1476
A multiplasmid approach to preparing large libraries of polyketides.
@en
P2093
P2860
P304
11740-11745
P356
10.1073/PNAS.96.21.11740
P407
P577
1999-10-01T00:00:00Z