Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
about
Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism.Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin.Manipulating natural product biosynthetic pathways via DNA assembler.Total syntheses and biological reassessment of lactimidomycin, isomigrastatin and congener glutarimide antibiotics.Artificial chromosomes to explore and to exploit biosynthetic capabilities of actinomycetes.Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners.Refactoring the silent spectinabilin gene cluster using a plug-and-play scaffold.Strain-level diversity of secondary metabolism in Streptomyces albusSTIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression.Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins.Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulationInsights into naturally minimised Streptomyces albus J1074 genome.Strain improvement in actinomycetes in the postgenomic era.Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters.Alternative hosts for functional (meta)genome analysis.A Long-Range Acting Dehydratase Domain as the Missing Link for C17-Dehydration in Iso-Migrastatin Biosynthesis.Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.A designer bleomycin with significantly improved DNA cleavage activity.Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.Biosynthesis of polyketides by trans-AT polyketide synthases.Titer improvement of iso-migrastatin in selected heterologous Streptomyces hosts and related analysis of mRNA expression by quantitative RT-PCR.Unusual site-specific DNA integration into the highly active pseudo-attB of the Streptomyces albus J1074 genome.Iso-migrastatin Titer Improvement in the Engineered Streptomyces lividans SB11002 Strain by Optimization of Fermentation Conditions.Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns.Focused Review: Cytotoxic and Antioxidant Potentials of Mangrove-Derived Streptomyces.Iterative marker excision system.The Immunosuppressant Brasilicardin: Determination of the Biosynthetic Gene Cluster in the Heterologous Host Amycolatopsis japonicum.Genome rearrangements of Streptomyces albus J1074 lead to the carotenoid gene cluster activation.
P2860
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P2860
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
@ast
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
@en
type
label
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
@ast
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
@en
prefLabel
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
@ast
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
@en
P2093
P2860
P1476
Engineered production of iso-migrastatin in heterologous Streptomyces hosts.
@en
P2093
Liyan Wang
Marie F Coeffet-LeGal
Scott R Rajski
Zhiyang Feng
P2860
P304
P356
10.1016/J.BMC.2008.10.074
P407
P50
P577
2008-11-05T00:00:00Z