Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling. - Test2 - elhamkhani - TriplyDB

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.

http://www.wikidata.org/entity/Q33242349

about

Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair DNA nucleotide excision repair-dependent signaling to checkpoint activation Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1 Cdc7-Dbf4 and the human S checkpoint response to UVC The DNA Damage Response: Making It Safe to Play with Knives Specific and efficient binding of xeroderma pigmentosum complementation group A to double-strand/single-strand DNA junctions with 3'- and/or 5'-ssDNA branches.Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A.Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice.Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links.Localization of xeroderma pigmentosum group A protein and replication protein A on damaged DNA in nucleotide excision repair.Effects of non-thermal plasma on mammalian cells.Postreplication gaps at UV lesions are signals for checkpoint activation.DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair.Effects of Tet-mediated oxidation products of 5-methylcytosine on DNA transcription in vitro and in mammalian cells.Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II.Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA.PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA.DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents.Induction of a G1-S checkpoint in fission yeast Non-transcriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis.Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically incorporated DNA lesions in vitro and in vivo Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts.Human DNA polymerase eta activity and translocation is regulated by phosphorylation.DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals.The Functions of Serine 687 Phosphorylation of Human DNA Polymerase η in UV Damage Tolerance.Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system.The human intra-S checkpoint response to UVC-induced DNA damage.DNA polymerase eta and chemotherapeutic agents.Mind the gap: keeping UV lesions in check.

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P2860

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.

http://www.wikidata.org/entity/Q33242349

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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Opposing effects of the UV les ...... a on ATR checkpoint signaling.

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Opposing effects of the UV les ...... a on ATR checkpoint signaling.

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Opposing effects of the UV les ...... a on ATR checkpoint signaling.

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Opposing effects of the UV les ...... a on ATR checkpoint signaling.

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Opposing effects of the UV les ...... a on ATR checkpoint signaling.

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Opposing effects of the UV les ...... a on ATR checkpoint signaling.

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SJ.EMBOJ.7601123

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The EMBO Journal

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Opposing effects of the UV les ...... a on ATR checkpoint signaling.

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P2093

Deena V Soni

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Karlene A Cimprich

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Muh-Ching Yee

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Patrick J Lupardus

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Ryan D Bomgarden

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P2860

A role for ATR in the DNA damage-induced phosphorylation of p53

Transcription promotes contraction of CAG repeat tracts in human cells

Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesis

ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation

UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

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16675950

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