Strain improvement in actinomycetes in the postgenomic era.
about
Antibacterial Discovery and Development: From Gene to Product and BackExploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproductionMicrobial genome mining for accelerated natural products discovery: is a renaissance in the making?Antibiotics and bacterial resistance in the 21st century.Platforms for antibiotic discovery.Culturable rare Actinomycetes: diversity, isolation and marine natural product discovery.Generation and study of the strains of streptomycetes - heterologous hosts for production of moenomycin.A novel Streptomyces spp. integration vector derived from the S. venezuelae phage, SV1Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024.The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraeaActivation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes.Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin.Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery.Streptomyces temperate bacteriophage integration systems for stable genetic engineering of actinomycetes (and other organisms).New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters.Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements.Strategies for mining fungal natural products.New applications for phage integrases.Spontaneous and induced mutations to rifampicin, streptomycin and spectinomycin resistances in actinomycetes: mutagenic mechanisms and applications for strain improvement.The Gene bldA, a regulator of morphological differentiation and antibiotic production in streptomyces.Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.Engineering microbial hosts for production of bacterial natural productsActivation and identification of five clusters for secondary metabolites in Streptomyces albus J1074.Insights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.Non-ribosomal peptide synthetases: Identifying the cryptic gene clusters and decoding the natural product.Molecular beacons to identify gifted microbes for genome mining.Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics.rRNA (rrn) operon-engineered Bacillus subtilis as a feasible test organism for antibiotic discoveryLincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis.Genome mining-directed activation of a silent angucycline biosynthetic gene cluster in Streptomyces chattanoogensis.Focused Review: Cytotoxic and Antioxidant Potentials of Mangrove-Derived Streptomyces.Actinomycetes: still a source of novel antibiotics.Genetic engineering of Streptomyces bingchenggensis to produce milbemycins A3/A4 as main components and eliminate the biosynthesis of nanchangmycin.Mutagenesis breeding of high echinocandin B producing strain and further titer improvement with culture medium optimization.Enhanced production of phenazine-like metabolite produced by Streptomyces aurantiogriseus VSMGT1014 against rice pathogen, Rhizoctonia solani.New Deferoxamine Glycoconjugates Produced upon Overexpression of Pathway-Specific Regulatory Gene in the Marine Sponge-Derived Streptomyces albus PVA94-07.Gifted microbes for genome mining and natural product discovery.MbtH homology codes to identify gifted microbes for genome mining.
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Strain improvement in actinomycetes in the postgenomic era.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 January 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Strain improvement in actinomycetes in the postgenomic era.
@en
Strain improvement in actinomycetes in the postgenomic era.
@nl
type
label
Strain improvement in actinomycetes in the postgenomic era.
@en
Strain improvement in actinomycetes in the postgenomic era.
@nl
prefLabel
Strain improvement in actinomycetes in the postgenomic era.
@en
Strain improvement in actinomycetes in the postgenomic era.
@nl
P2860
P1476
Strain improvement in actinomycetes in the postgenomic era.
@en
P2093
Richard H Baltz
P2860
P304
P356
10.1007/S10295-010-0934-Z
P577
2011-01-21T00:00:00Z