Inhibitors of human tyrosyl-DNA phospodiesterase (hTdp1) developed by virtual screening using ligand-based pharmacophores.
about
Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening MethodologiesSynthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1)Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.Structure Modeling of Human Tyrosyl-DNA Phosphodiesterase 1 and Screening for Its Inhibitors.Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecanTDP1/TOP1 Ratio as a Promising Indicator for the Response of Small Cell Lung Cancer to Topotecan.Mechanism-informed Repurposing of Minocycline Overcomes Resistance to Topoisomerase Inhibition for Peritoneal Carcinomatosis.The Human Tyrosyl-DNA Phosphodiesterase 1 (hTdp1) Inhibitor NSC120686 as an Exploratory Tool to Investigate Plant Tdp1 Genes.
P2860
Q26745421-D6439934-5FEC-4AEA-8FB5-3AB39E1ADB7DQ36524994-B882EEA4-D2F2-4E17-8CE3-9C03FF463A99Q38261264-956B2FD1-5A71-45AD-9975-D02249A2E470Q38287674-01E12145-BC3D-45E5-9732-2DBA72EED97BQ38927275-720A97D1-BEBE-4A66-B7B0-4F6F88FF0AE9Q41959085-D19E1D19-EF74-482A-9DCE-1F417250D247Q49788115-60B66BA0-E8C6-4A55-AF02-A009C5CD6852Q55340676-9FB7FF13-ECC7-41D6-AF2A-875A7EDA64D0
P2860
Inhibitors of human tyrosyl-DNA phospodiesterase (hTdp1) developed by virtual screening using ligand-based pharmacophores.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Inhibitors of human tyrosyl-DN ...... g ligand-based pharmacophores.
@ast
Inhibitors of human tyrosyl-DN ...... g ligand-based pharmacophores.
@en
Inhibitors of human tyrosyl-DNA phospodiesterase
@nl
type
label
Inhibitors of human tyrosyl-DN ...... g ligand-based pharmacophores.
@ast
Inhibitors of human tyrosyl-DN ...... g ligand-based pharmacophores.
@en
Inhibitors of human tyrosyl-DNA phospodiesterase
@nl
prefLabel
Inhibitors of human tyrosyl-DN ...... g ligand-based pharmacophores.
@ast
Inhibitors of human tyrosyl-DN ...... g ligand-based pharmacophores.
@en
Inhibitors of human tyrosyl-DNA phospodiesterase
@nl
P2093
P2860
P1476
Inhibitors of human tyrosyl-DN ...... g ligand-based pharmacophores.
@en
P2093
Christophe Marchand
Iwona E Weidlich
Smitha Antony
Thomas Dexheimer
P2860
P304
P356
10.1016/J.BMC.2009.11.008
P407
P577
2009-11-11T00:00:00Z