DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2. - Test2 - elhamkhani - TriplyDB

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

http://www.wikidata.org/entity/Q33681983

about

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1 Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication DNA End Resection: Facts and Mechanisms Nucleases in homologous recombination as targets for cancer therapy Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae TOPping off meiosis Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity Sources of DNA double-strand breaks and models of recombinational DNA repair The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes DNA dynamics during early double-strand break processing revealed by non-intrusive imaging of living cells Single-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding.Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single-molecule imaging Emerging critical roles of Fe-S clusters in DNA replication and repair.Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair Crystal structure of the NurA-dAMP-Mn2+ complex Structural and functional insights into DNA-end processing by the archaeal HerA helicase-NurA nuclease complex Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling End-resection at DNA double-strand breaks in the three domains of life Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.Dna2 exhibits a unique strand end-dependent helicase function.Nuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity.Hst3 and Hst4 histone deacetylases regulate replicative lifespan by preventing genome instability in Saccharomyces cerevisiae.The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends.Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.Homologous recombination via synthesis-dependent strand annealing in yeast requires the Irc20 and Srs2 DNA helicases.Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity EXD2 promotes homologous recombination by facilitating DNA end resection Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctions Microhomology-mediated end joining: new players join the team Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.A DNA2 Homolog Is Required for DNA Damage Repair, Cell Cycle Regulation, and Meristem Maintenance in Plants.Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.

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DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

http://www.wikidata.org/entity/Q33681983

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

@ast

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

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type

label

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

@ast

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

@en

prefLabel

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

@ast

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

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DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

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P2093

Elda Cannavo

http://www.w3.org/2001/XMLSchema#string

Judith L Campbell

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Petr Cejka

http://www.w3.org/2001/XMLSchema#string

Piotr Polaczek

http://www.w3.org/2001/XMLSchema#string

Stephen C Kowalczykowski

http://www.w3.org/2001/XMLSchema#string

Subhash Pokharel

http://www.w3.org/2001/XMLSchema#string

Taro Masuda-Sasa

http://www.w3.org/2001/XMLSchema#string

P2860

RecBCD enzyme and the repair of double-stranded DNA breaks

Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing.

DNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes.

Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.

RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex

The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51

Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

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112-116

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scholarly article

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10.1038/NATURE09355

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7311

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467

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2010-09-01T00:00:00Z

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46111179

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1049775672

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20811461

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3089589

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