Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage - Test2 - elhamkhani - TriplyDB

Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage

Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage

http://www.wikidata.org/entity/Q33888520

about

Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates An overview of Cdk1-controlled targets and processes Collaborator of ARF (CARF) regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Common mechanisms of PIKK regulation The DNA Damage Response: Making It Safe to Play with Knives Regulation of budding yeast mating-type switching donor preference by the FHA domain of Fkh1 Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment ATR: an essential regulator of genome integrity Poetry in motion: Increased chromosomal mobility after DNA damage.A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae.CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance.Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9-Hus1-Rad1 complex at stalled replication forks Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts.The viral oncoprotein tax sequesters DNA damage response factors by tethering MDC1 to chromatin.The Rad4(TopBP1) ATR-activation domain functions in G1/S phase in a chromatin-dependent manner.The histone H4 lysine 20 monomethyl mark, set by PR-Set7 and stabilized by L(3)mbt, is necessary for proper interphase chromatin organization.Cdc5 blocks in vivo Rad53 activity, but not in situ activity (ISA).Activation of DNA damage response signaling by condensed chromatin.Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1)Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanism Regulation of Mec1 kinase activity by the SWI/SNF chromatin remodeling complex The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint.Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae Heterochromatin formation via recruitment of DNA repair proteins.Curcumin-Mediated HDAC Inhibition Suppresses the DNA Damage Response and Contributes to Increased DNA Damage Sensitivity.Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo.A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma The emerging role of nuclear architecture in DNA repair and genome maintenance.Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection.Dpb11 activates the Mec1-Ddc2 complex DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.Molecular basis of the essential s phase function of the rad53 checkpoint kinase.Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA.Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage.Engineering a DNA damage response without DNA damage.

P2860

Q21076125-99B251DC-2A52-401C-A550-BABBEC2C9767 Q21203553-DFA3CCE5-1AE0-4C0E-9543-0CE311A35817 Q24297805-24C6116F-6ED7-470E-B61D-13BC9D7B8A9C Q24317544-5F47EE4F-817F-43BA-BF89-F1B67DA6D62E Q24608343-4A0F3A88-7644-427E-98A2-B793A579F34D Q24653672-FAE3E866-69E0-49A9-BFBF-5ACB27B5C0F3 Q27861055-7E36E8EC-4E4B-4C46-8C4A-934252F9CFA4 Q27936144-4897EF57-D046-4D22-87EE-4C16A4655BF5 Q27937150-5878A8DE-B016-4E1D-BB1B-810D55672A16 Q29547883-814FB1F7-0046-4EB7-97F4-67A342B80940 Q33470805-23BD83DC-6CED-4415-8D17-04F9985F3077 Q33522877-A80D975D-C323-479D-89B2-7BA108E49ADC Q33528933-1199AFD3-62A9-4FA2-BAD1-B77E3D8D719B Q33649550-30535E91-D58C-4B38-BD63-DBDBEE39180F Q33721233-9A26A0B7-ABFB-457D-86A7-5CDFADF01F30 Q34047330-3C8A6335-FC48-4D61-B806-AF5E09DDF059 Q34107375-4B5FE7BD-45DD-4AAF-BDFE-1F684469BF85 Q34236779-39ECAADF-8117-4ACB-AF7D-03B6A3371E96 Q34325590-DD76B111-8FD4-44A7-97B8-CDB4CB9E2338 Q34425328-5395A16D-CBAF-4FD1-B40B-0D837770E2E6 Q34659809-139C1887-3C69-4FB6-85A5-FE5A41DCEA54 Q34713712-634032DA-1EE4-454B-8D72-89BF4789417D Q35010875-F0BA070D-1202-4D12-82D4-D7EF680A231F Q35105714-B5BF1E65-C0F9-40E7-9C5D-881662036DF2 Q35228735-693D7AE0-0BA1-4CB5-A230-0E9E53A190FA Q35562444-3A714FC0-B287-461B-9B56-22889657599E Q35568186-142A7AAC-BF3F-4994-BD80-3D50AF35B3BE Q35679278-FE52F59B-1640-41AC-AB4F-924D88352CDC Q35719387-577BFDE2-2E1F-4EA7-99F7-73D5041FB954 Q35827500-29B99D4A-BB4C-4F81-8EAD-AFFC01B4CA67 Q36105987-91202485-A254-4852-A04C-5A72421D0AE1 Q36340722-A2FB7C35-5868-475B-8186-DEEBB3B5C33E Q36621898-1542C6F7-1A99-4D8A-B538-9BF0A522318D Q36775519-057DF658-2BBE-4E38-84F5-94478C4548BF Q36999901-EC988263-836D-46DF-935B-6C309CB77E49 Q37056627-9AA34C6A-FB70-4D35-AC9E-0FC709E9F892 Q37122913-56021988-A91C-4AAF-BB83-1C1549189B74 Q37128106-0B49425F-8D05-43F9-8B8E-4903A8A80D25 Q37220138-E3A94AA4-900D-4849-8921-EF52ECA3DABF Q37232111-58564F01-759D-4545-A075-313F720CF54B

P2860

Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage

http://www.wikidata.org/entity/Q33888520

description

2008 nî lūn-bûn

@nan

2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Colocalization of sensors is s ...... point in the absence of damage

@ast

Colocalization of sensors is s ...... point in the absence of damage

@en

type

label

Colocalization of sensors is s ...... point in the absence of damage

@ast

Colocalization of sensors is s ...... point in the absence of damage

@en

prefLabel

Colocalization of sensors is s ...... point in the absence of damage

@ast

Colocalization of sensors is s ...... point in the absence of damage

@en

P1433

Q33888520-C93A0781-BABA-45AD-A9E5-F30FF2A51D13

P1476

Q33888520-05DD3015-C3CD-402D-B26C-F71414C9C088

P2093

Q33888520-255A104E-CCBD-40AD-9538-0A8CB7B6495D

Q33888520-51ABDAA2-FDF2-4910-B295-E0C8EF79E634

Q33888520-C5D19982-8DC1-4850-A2C4-CF588C4CC40E

P2860

Q33888520-01962DCF-680E-48D7-BAD0-375CA90F061E

Q33888520-09437ED9-7B8A-4902-9140-8AF2D06D53EA

Q33888520-0EF23A7C-FCBA-4530-81F6-9A0E52258D75

Q33888520-0F2B8B0E-79EB-4200-97A4-B56E128D8CF1

Q33888520-164D5F21-154F-4B99-87EE-7C92D8587F0D

Q33888520-1970266F-61B7-4AF9-ADCC-D6FCE11B2A22

Q33888520-21E7166B-0A32-46EC-A433-E16352322D6D

Q33888520-29C52B87-22C9-4D65-AC43-98AF42D5E2DC

Q33888520-2E51E320-9225-4D28-B3CB-A0A4E92A1814

Q33888520-324A15CA-30AF-40E6-B6ED-20CF88797977

P304

Q33888520-12EF5EEC-9F7F-4ED8-A7D5-1774271416B1

P31

Q33888520-BECC78AF-DA66-44D1-9C2E-699FEBF6E5D6

P356

Q33888520-C0A93F65-87A5-4D29-8346-814D6A5D0728

P433

Q33888520-62B9F069-9B3A-49B9-8527-1BE4E6EF1298

P478

Q33888520-15A20DCB-CDBA-4BA7-A7FF-F2EC4C9E093D

P577

Q33888520-E315B4E8-F311-452A-88F6-8715FA38CCF3

P5875

Q33888520-646722A7-F743-4F2E-BDD5-03264C1F029E

P698

Q33888520-C063E1CA-1BCD-4561-9615-D8527CBE929C

P921

Q33888520-2833483D-77C2-4D72-9435-01F5BA8FCF8F

P932

Q33888520-A9A62950-9D4C-447D-805B-AECDBEE5ED9C

P356

J.MOLCEL.2008.03.023

P1433

P1476

Colocalization of sensors is s ...... point in the absence of damage

@en

P2093

Carla Yaneth Bonilla

http://www.w3.org/2001/XMLSchema#string

David Paul Toczyski

http://www.w3.org/2001/XMLSchema#string

Justine Amy Melo

http://www.w3.org/2001/XMLSchema#string

P2860

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

Replication protein A-mediated recruitment and activation of Rad17 complexes

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast.

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

P304

267-276

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.MOLCEL.2008.03.023

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

30

http://www.w3.org/2001/XMLSchema#string

P577

2008-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5379557

http://www.w3.org/2001/XMLSchema#string

P698

18471973

http://www.w3.org/2001/XMLSchema#string

P921

P932

2879338

http://www.w3.org/2001/XMLSchema#string