Identification and characterization of novel sirtuin inhibitor scaffolds - Test2 - elhamkhani - TriplyDB

Identification and characterization of novel sirtuin inhibitor scaffolds

Identification and characterization of novel sirtuin inhibitor scaffolds

http://www.wikidata.org/entity/Q34088797

about

MYST protein acetyltransferase activity requires active site lysine autoacetylation Rejuvenating sirtuins: the rise of a new family of cancer drug targets Writers and readers of histone acetylation: structure, mechanism, and inhibition Histone deacetylase inhibitors (HDACIs). Structure--activity relationships: history and new QSAR perspectives.Sirtuin 1 (SIRT1): the misunderstood HDAC.Schistosome sirtuins as drug targets.Use of the Monte Carlo Method for OECD Principles-Guided QSAR Modeling of SIRT1 Inhibitors.Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products.

P2860

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P2860

Identification and characterization of novel sirtuin inhibitor scaffolds

http://www.wikidata.org/entity/Q34088797

description

2009 nî lūn-bûn

@nan

2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Identification and characterization of novel sirtuin inhibitor scaffolds

@ast

Identification and characterization of novel sirtuin inhibitor scaffolds

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Identification and characterization of novel sirtuin inhibitor scaffolds

@nl

type

label

Identification and characterization of novel sirtuin inhibitor scaffolds

@ast

Identification and characterization of novel sirtuin inhibitor scaffolds

@en

Identification and characterization of novel sirtuin inhibitor scaffolds

@nl

prefLabel

Identification and characterization of novel sirtuin inhibitor scaffolds

@ast

Identification and characterization of novel sirtuin inhibitor scaffolds

@en

Identification and characterization of novel sirtuin inhibitor scaffolds

@nl

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J.BMC.2009.07.073

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Bioorganic & Medicinal Chemistry

P1476

Identification and characterization of novel sirtuin inhibitor scaffolds

@en

P2093

Alexander M Taylor

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Brandi D Sanders

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Brittany Jackson

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Konrad Howitz

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Michael Brent

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Ronen Marmorstein

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Stuart L Schreiber

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Weiwei Dang

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P2860

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Structure and autoregulation of the yeast Hst2 homolog of Sir2

Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin

The fundamental role of epigenetic events in cancer

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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7031-7041

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10.1016/J.BMC.2009.07.073

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Shelley L. Berger

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