PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
about
Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersRole of Retinoic Acid-Metabolizing Cytochrome P450s, CYP26, in Inflammation and CancerEpigenomics of leukemia: from mechanisms to therapeutic applicationsEpigenomics of cancer - emerging new conceptsThe cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodiesMechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O 3) in acute promyelocytic leukemia.Genome-wide epigenomic profiling for biomarker discoveryBET domain co-regulators in obesity, inflammation and cancerCharacterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individualsArsenic sulfide promotes apoptosis in retinoid acid resistant human acute promyelocytic leukemic NB4-R1 cells through downregulation of SET proteinCistrome plasticity and mechanisms of cistrome reprogrammingThe European Hematology Association Roadmap for European Hematology Research: a consensus documentThe class I-specific HDAC inhibitor MS-275 modulates the differentiation potential of mouse embryonic stem cells.HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapseMeeting report: nuclear receptors: transcription factors and drug targets connecting basic research with translational medicine.Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome.Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemiaBiological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding.Affinity-based enrichment strategies to assay methyl-CpG binding activity and DNA methylation in early Xenopus embryos.Characterisation of genome-wide PLZF/RARA target genes.Discovering chromatin motifs using FAIRE sequencing and the human diploid genomePU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells.Filamins but not Janus kinases are substrates of the ASB2α cullin-ring E3 ubiquitin ligase in hematopoietic cells.Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA miceBromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammationAberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune diseaseHomeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations.Sparse expression bases in cancer reveal tumor drivers.New role for granulocyte colony-stimulating factor-induced extracellular signal-regulated kinase 1/2 in histone modification and retinoic acid receptor α recruitment to gene promoters: relevance to acute promyelocytic leukemia cell differentiation.Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesisFunctional and structural insights into ASB2alpha, a novel regulator of integrin-dependent adhesion of hematopoietic cellsCoactivation of GR and NFKB alters the repertoire of their binding sites and target genes.The decade of the epigenomes?Dominant-negative mechanism of leukemogenic PAX5 fusions.Epigenetic regulation by RARα maintains ligand-independent transcriptional activity.RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements.Antagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cellsAntileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy.Impact of vitamin D metabolism on clinical epigenetics.
P2860
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P2860
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@ast
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@en
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@nl
type
label
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@ast
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@en
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@nl
prefLabel
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@ast
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@en
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.
@nl
P2093
P50
P1433
P1476
PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia
@en
P2093
Felicetto Ferrara
Femke Simmer
Hendrik G Stunnenberg
Kees-Jan Francoijs
P304
P356
10.1016/J.CCR.2009.12.042
P577
2010-02-01T00:00:00Z