Bcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motif
about
BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreSynthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site.Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737Cytosolic BNIP3 Dimer Interacts with Mitochondrial BAX Forming Heterodimers in the Mitochondrial Outer Membrane under Basal Conditions.Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xLAn Integrated Bioinformatics and Computational Biology Approach Identifies New BH3-Only Protein CandidatesAfter embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization.Natural polyphenolic inhibitors against the antiapoptotic BCL-2.Hugl-1 induces apoptosis in esophageal carcinoma cells both in vitro and in vivo.A unified model of mammalian BCL-2 protein family interactions at the mitochondria.Modulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum-Mitochondrial Interface.The role of RhoC in the proliferation and apoptosis of hepatocellular carcinoma cells.An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.The N-terminal helix of Bcl-xL targets mitochondria.Boletus edulis ribonucleic acid - a potent apoptosis inducer in human colon adenocarcinoma cells.Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis.Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation.Structural model of active Bax at the membrane.Activation of Casein Kinase II by Gallic Acid Induces BIK-BAX/BAK-Mediated ER Ca++-ROS-Dependent Apoptosis of Human Oral Cancer Cells.Insights into the structural stability of Bax from molecular dynamics simulations at high temperatures.A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function.Complex disruption effect of natural polyphenols on Bcl-2-Bax: molecular dynamics simulation and essential dynamics study.Linear and Cyclic Depsipeptidomimetics with β-Lactam Cores: A Class of New αv β3 Integrin Receptor Inhibitors.Multisite phosphorylation of Bcl-2 via protein kinase Cδ facilitates apoptosis of hypertrophic cardiomyocytes.Baicalein ameliorates renal interstitial fibrosis by inducing myofibroblast apoptosis in vivo and in vitro.Cyclic RGD β-Lactam Peptidomimetics Induce Differential Gene Expression in Human Endothelial Cells
P2860
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P2860
Bcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motif
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@ast
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@en
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@nl
type
label
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@ast
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@en
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@nl
prefLabel
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@ast
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@en
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@nl
P2093
P2860
P356
P1476
Bcl-2 and Bax interact via the ...... erface involving the BH4 motif
@en
P2093
G Jane Roberts
Jialing Lin
Jingzhen Ding
Mina Falcone
Xuejun C Zhang
Yiwei Miao
Yuanlong Shao
P2860
P304
28749-28763
P356
10.1074/JBC.M110.148361
P407
P577
2010-06-28T00:00:00Z