The ubiquitin-proteasome system: opportunities for therapeutic intervention in solid tumors
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Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genesSesterterpenoids with Anticancer ActivityTargeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein HomeostasisThe novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibitionCombination of bortezomib and daunorubicin in the induction of apoptosis in T-cell acute lymphoblastic leukemiaMisfolded proteins: from little villains to little helpers in the fight against cancer.Dissecting the regulation rules of cancer-related miRNAs based on network analysis.Original Research: Featured Article: Imatinib mesylate (Gleevec) inhibits Notch and c-Myc signaling: Five-day treatment permanently rescues mammary development.Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis.Novel investigational therapies for treating biliary tract carcinoma.Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future.The evaluation of the anti-cancer activity of ixazomib on Caco2 colon solid tumor cells, comparison with bortezomib.The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug TargetHepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame.Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.Colonic Lamina Propria Inflammatory Cells from Patients with IBD Induce the Nuclear Factor-E2 Related Factor-2 Thereby Leading to Greater Proteasome Activity and Apoptosis Protection in Human Colonocytes.Milder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events.Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies.FBXO4 inhibits lung cancer cell survival by targeting Mcl-1 for degradation.Targeting Deubiquitinating Enzymes and Autophagy in Cancer.Nanoparticles Exacerbate Both Ubiquitin and Heat Shock Protein Expressions in Spinal Cord Injury: Neuroprotective Effects of the Proteasome Inhibitor Carfilzomib and the Antioxidant Compound H-290/51.Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.Role of the ubiquitin/proteasome system on ACTH turnover in rat corticotropes.2-Aminoethoxydiphenylborane sensitizes anti-tumor effect of bortezomib via suppression of calcium-mediated autophagy.BAP1 acts as a tumor suppressor in intrahepatic cholangiocarcinoma by modulating the ERK1/2 and JNK/c-Jun pathways
P2860
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P2860
The ubiquitin-proteasome system: opportunities for therapeutic intervention in solid tumors
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@ast
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@en
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@nl
type
label
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@ast
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@en
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@nl
prefLabel
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@ast
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@en
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@nl
P2860
P356
P1476
The ubiquitin-proteasome syste ...... c intervention in solid tumors
@en
P2093
Daniel E Johnson
P2860
P356
10.1530/ERC-14-0005
P577
2014-03-21T00:00:00Z