The fragile X syndrome: exploring its molecular basis and seeking a treatment.
about
On the aggregation properties of FMRP--a link with the FXTAS syndrome?Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolinNuclear Fragile X Mental Retardation Protein is localized to Cajal bodiesA novel function for fragile X mental retardation protein in translational activationFragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampusFragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structureDendritic mRNA targeting of Jacob and N-methyl-d-aspartate-induced nuclear translocation after calpain-mediated proteolysisThe fragile X mental retardation protein interacts with a distinct mRNA nuclear export factor NXF2Regulation of GABAA receptors by fragile X mental retardation proteinNXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins.A mouse model of the human Fragile X syndrome I304N mutation.Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.Global signatures of protein and mRNA expression levels.Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected].Increasing our understanding of human cognition through the study of Fragile X Syndrome.Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.The fragile x mental retardation syndrome 20 years after the FMR1 gene discovery: an expanding universe of knowledge.A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse modelFragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells.Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOROn BC1 RNA and the fragile X mental retardation protein.The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellumA study of the ultrastructure of fragile-X-related proteinsLongitudinal in vivo developmental changes of metabolites in the hippocampus of Fmr1 knockout miceA STEP forward in neural function and degeneration.RNA-binding proteins in neurological diseases.Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis.Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densitiesConformational-dependent and independent RNA binding to the fragile x mental retardation protein.Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma.The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?Molecular dynamics of FMRP and other RNA-binding proteins in MEG-01 differentiation: the role of mRNP complexes in non-neuronal development.Molecular diagnosis of Fragile X syndrome.Differential expression of Fmr-1 mRNA and FMRP in female mice brain during aging.New Insights Into the Role of Ca2 Protein Family in Calcium Flux Deregulation in -KO Neurons
P2860
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P2860
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@ast
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@en
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@nl
type
label
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@ast
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@en
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@nl
prefLabel
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@ast
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@en
The fragile X syndrome: exploring its molecular basis and seeking a treatment.
@nl
P2093
P1476
The fragile X syndrome: exploring its molecular basis and seeking a treatment
@en
P2093
Edouard W Khandjian
Laetitia Davidovic
Mounia Bensaid
P356
10.1017/S1462399406010751
P577
2006-04-21T00:00:00Z