DNA damage checkpoint control in cells exposed to ionizing radiation. - Test2 - elhamkhani - TriplyDB

DNA damage checkpoint control in cells exposed to ionizing radiation.

DNA damage checkpoint control in cells exposed to ionizing radiation.

http://www.wikidata.org/entity/Q35208818

about

The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.Characterization of a novel low-molecular-mass dual-specificity phosphatase-3 (LDP-3) that enhances activation of JNK and p38 Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells DNA and the chromosome - varied targets for chemotherapy Prion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage response Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53 Antioxidative dietary compounds modulate gene expression associated with apoptosis, DNA repair, inhibition of cell proliferation and migration In vivo characterization of early-stage radiation skin injury in a mouse model by two-photon microscopy Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1 DNA damage response genes and the development of cancer metastasis DMA, a bisbenzimidazole, offers radioprotection by promoting NFκB transactivation through NIK/IKK in human glioma cells Radiation therapy and cancer control in developing countries: Can we save more lives?A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance The enigmatic effects of caffeine in cell cycle and cancer Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition.Gefitinib radiosensitizes non-small cell lung cancer cells through inhibition of ataxia telangiectasia mutated.ATM-NF-kappaB connection as a target for tumor radiosensitization Inhibition of TFII-I-dependent cell cycle regulation by p53.SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT.Validation of the cell cycle G(2) delay assay in assessing ionizing radiation sensitivity and breast cancer risk.Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell lines.ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation.Inactivation of ATM/ATR DNA damage checkpoint promotes androgen induced chromosomal instability in prostate epithelial cells Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage.Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation.Reduced synchronization persistence in neural networks derived from atm-deficient mice.Exposure of human lung cancer cells to 8-chloro-adenosine induces G2/M arrest and mitotic catastrophe.Radiation-induced biomarkers for the detection and assessment of absorbed radiation doses MK-1775, a novel Wee1 kinase inhibitor, radiosensitizes p53-defective human tumor cells.Bora downregulation results in radioresistance by promoting repair of double strand breaks.Disorder of G2-M Checkpoint Control in Aniline-Induced Cell Proliferation in Rat Spleen.A comparison of the biological effects of 125I seeds continuous low-dose-rate radiation and 60Co high-dose-rate gamma radiation on non-small cell lung cancer cells.Chk1 Activation Protects Rad9A from Degradation as Part of a Positive Feedback Loop during Checkpoint Signalling.Protein expression pattern in response to ionizing radiation in MCF-7 human breast cancer cells.Computational modeling of signaling pathways mediating cell cycle checkpoint control and apoptotic responses to ionizing radiation-induced DNA damage.CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation.The diverse and complex roles of radiation on cancer treatment: therapeutic target and genome maintenance.DNA damage and osmotic regulation in the kidney.Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.

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DNA damage checkpoint control in cells exposed to ionizing radiation.

http://www.wikidata.org/entity/Q35208818

description

2003 nî lūn-bûn

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2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

DNA damage checkpoint control in cells exposed to ionizing radiation.

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DNA damage checkpoint control in cells exposed to ionizing radiation.

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type

label

DNA damage checkpoint control in cells exposed to ionizing radiation.

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DNA damage checkpoint control in cells exposed to ionizing radiation.

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prefLabel

DNA damage checkpoint control in cells exposed to ionizing radiation.

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DNA damage checkpoint control in cells exposed to ionizing radiation.

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DNA damage checkpoint control in cells exposed to ionizing radiation.

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P2093

George Iliakis

http://www.w3.org/2001/XMLSchema#string

Huichen Wang

http://www.w3.org/2001/XMLSchema#string

Jun Guan

http://www.w3.org/2001/XMLSchema#string

Ya Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex

A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease

Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

Purification and characterization of human DNA damage checkpoint Rad complexes

Myc and Max: molecular evolution of a family of proto-oncogene products and their dimerization partner

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition.

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

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5834-5847

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scholarly article

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10.1038/SJ.ONC.1206682

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37

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22

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2003-09-01T00:00:00Z

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10590639

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12947390

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