Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching. - Test2 - elhamkhani - TriplyDB

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching.

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching.

http://www.wikidata.org/entity/Q35220027

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Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor Targeting the Bromome: are we there yet?CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses BET inhibition as a new strategy for the treatment of gastric cancer.Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery Potent and selective bivalent inhibitors of BET bromodomains.ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma.The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.Frapid: achieving full automation of FRAP for chemical probe validation Progress in the Development of non-BET Bromodomain Chemical Probes.Cellular analysis of the action of epigenetic drugs and probes.Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex.The global cancer genomics consortium's symposium: new era of molecular medicine and epigenetic cancer medicine - cross section of genomics and epigenetics.Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple).Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition.

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Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching.

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2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Epigenetics & Chromatin

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Catherine M Rogers

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Chris Wells

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Claire Strain-Damerell

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Clarence Yapp

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Jean-Philippe Lambert

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Martin Philpott

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Nicola A Burgess-Brown

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P2860

RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition

Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5

Selective inhibition of BET bromodomains

Histone recognition and large-scale structural analysis of the human bromodomain family

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

TRIM24 links a non-canonical histone signature to breast cancer

ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression

Human ORFeome version 1.1: a platform for reverse proteomics

Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis

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Anne-Claude Gingras

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