Nuclear transport and cancer: from mechanism to intervention.
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Camptothecin induces nuclear export of prohibitin preferentially in transformed cells through a CRM-1-dependent mechanismThe second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and functionAnalysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).Nuclear translocation of beta-dystroglycan reveals a distinctive trafficking pattern of autoproteolyzed mucinsTopology of yeast Ndc1p: predictions for the human NDC1/NET3 homologueCharacterization of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systemsA high-throughput screening of genes that encode proteins transported into the endoplasmic reticulum in mammalian cellsMechanisms of Nuclear Export in Cancer and Resistance to ChemotherapyNuclear transport of galectin-3 and its therapeutic implicationsNew targets for the antitumor activity of gambogic acid in hematologic malignanciesNuclear export of proteins and drug resistance in cancerBy moonlighting in the nucleus, villin regulates epithelial plasticity.Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemiap53-Dependent anticancer effects of leptomycin B on lung adenocarcinomaDiscovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic ShuttlingPhosphorylation of dystrophin Dp71d by Ca2+/calmodulin-dependent protein kinase II modulates the Dp71d nuclear localization in PC12 cellsNuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.Nuclear export of NBN is required for normal cellular responses to radiationSTRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7.The functionally conserved nucleoporins Nup124p from fission yeast and the human Nup153 mediate nuclear import and activity of the Tf1 retrotransposon and HIV-1 Vpr.Transient nuclear envelope rupturing during interphase in human cancer cells.A foundation for reliable spatial proteomics data analysis.Inference of dynamic networks using time-course data.Mass-spectrometry-based spatial proteomics data analysis using pRoloc and pRolocdata.On the statistical assessment of classifiers using DNA microarray data.First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid TumorsIdentification of essential sequences for cellular localization in BRMS1 metastasis suppressor.Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patientsKaryopherin alpha 2 expression is a novel diagnostic and prognostic factor for colorectal cancerHmga2 translocation induced in skin tumorigenesis.Determining the distribution of probes between different subcellular locations through automated unmixing of subcellular patterns.Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding.Deciphering the folding transition state structure and denatured state properties of nucleophosmin C-terminal domain.KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cellsOridonin induces NPM mutant protein translocation and apoptosis in NPM1c+ acute myeloid leukemia cells in vitro.The molecular mechanism for nuclear transport and its application.Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma.Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by deregulating the expression of AR and CXCR4.Pleomorphic adenoma gene 1 mediates the role of karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma.Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes.
P2860
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P2860
Nuclear transport and cancer: from mechanism to intervention.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Nuclear transport and cancer: from mechanism to intervention.
@ast
Nuclear transport and cancer: from mechanism to intervention.
@en
type
label
Nuclear transport and cancer: from mechanism to intervention.
@ast
Nuclear transport and cancer: from mechanism to intervention.
@en
prefLabel
Nuclear transport and cancer: from mechanism to intervention.
@ast
Nuclear transport and cancer: from mechanism to intervention.
@en
P2860
P356
P1476
Nuclear transport and cancer: from mechanism to intervention.
@en
P2093
Jeffrey C Way
Tweeny R Kau
P2860
P2888
P304
P356
10.1038/NRC1274
P407
P577
2004-02-01T00:00:00Z