MafA and MafB regulate genes critical to beta-cells in a unique temporal manner - Test2 - elhamkhani - TriplyDB

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

http://www.wikidata.org/entity/Q35757141

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Generation of β cells from human pluripotent stem cells: are we there yet?Derivation of insulin-producing beta-cells from human pluripotent stem cells Transcription factor regulation of pancreatic organogenesis, differentiation and maturation The B55α-containing PP2A holoenzyme dephosphorylates FOXO1 in islet β-cells under oxidative stress Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma High-content screening identifies a role for Na(+) channels in insulin production Cdc42/N-WASP signaling links actin dynamics to pancreatic β cell delamination and differentiation.Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and culture The MafA transcription factor becomes essential to islet β-cells soon after birth.Raptor regulates functional maturation of murine beta cells.Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions.Minireview: Thioredoxin-interacting protein: regulation and function in the pancreatic β-cell.MafA is required for postnatal proliferation of pancreatic β-cells.Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.Pancreatic transcription factors containing protein transduction domains drive mouse embryonic stem cells towards endocrine pancreas Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA Islet-1 Is essential for pancreatic β-cell function.Reprogramming of human pancreatic exocrine cells to β-like cells.Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate.Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.Sox9: a master regulator of the pancreatic program.Maturation of stem cell-derived beta-cells guided by the expression of urocortin 3.Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes.Initial cell seeding density influences pancreatic endocrine development during in vitro differentiation of human embryonic stem cells.Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions.Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells.Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in mice Generation of insulin-producing cells from the mouse liver using β cell-related gene transfer including Mafa and Mafb.Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets.Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker Organogenesis and functional genomics of the endocrine pancreas β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.Deconstructing pancreas developmental biology.DNA methylation directs functional maturation of pancreatic β cells.The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression.Concise Review: Markers for Assessing Human Stem Cell-Derived Implants as β-Cell Replacement in Type 1 Diabetes.

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MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

http://www.wikidata.org/entity/Q35757141

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

@zh-tw

2010年论文

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2010年论文

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2010年论文

@zh-cn

name

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

@ast

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

@en

type

label

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

@ast

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

@en

prefLabel

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

@ast

MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

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MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

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P2093

Magdalena Mazur

http://www.w3.org/2001/XMLSchema#string

Min Guo

http://www.w3.org/2001/XMLSchema#string

Roland Stein

http://www.w3.org/2001/XMLSchema#string

Tsunehiko Yamamoto

http://www.w3.org/2001/XMLSchema#string

Yan Hang

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

The myoD gene family: nodal point during specification of the muscle cell lineage

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression

MafB is required for islet beta cell maturation

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

A genome-wide association study identifies novel risk loci for type 2 diabetes

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia

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2530-2539

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10.2337/DB10-0190

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10

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59

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Isabella Artner

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2010-07-13T00:00:00Z

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45185172

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20627934

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3279542

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